The present study was performed in order to examine the composition of the connective tissue that forms an attachment to a dental implant. 6 beagle dogs were used. All mandibular premolars were extracted. After 3 months of healing, 6 fixtures – 3 in each side of the mandible – (Astra Tech Implants, Dental SystemA TiO blast ; Astra Tech AB, Mölndal, Sweden) were installed. After another 3 months...

The Ca(2+)-switch technique was used to investigate the nature of the barrier governing (paracellular) permeability across the junctions of "native" rabbit esophageal epithelium. This was done by mounting esophageal epithelium in Ussing chambers to monitor transepithelial electrical resistance (R(T)), a marker of junctional permeability. When exposed to Ca(2+)-free Ringer solutions containing E...

The junctional epithelium (JE) adheres to the tooth surface, and seals off periodontal tissues from the oral environment. This incompletely differentiated epithelium is formed initially by the fusion of the reduced enamel organ with the oral epithelium (OE). Two proteins, odontogenic ameloblast-associated (ODAM) and amelotin (AMTN), have been identified in the JE. The objective of this study wa...

AIM To describe histologically the early phases of soft tissue healing to implants placed into fresh extraction sockets. MATERIALS AND METHODS In 16 beagle dogs, 64 3.25-mm-wide cylindrical screw implants were inserted into the distal sockets of the third and fourth lower premolars using a one-stage trans-mucosal healing protocol. Biopsies were then taken at 1, 2, 4 and 8 weeks and prepared f...

Adenocarcinoma of the distal esophagus and gastroesophageal junction are believed to arise in Barrett's esophagus with intestinal metaplasia. Whether adenocarcinoma can arise in columnar lined esophagus without intestinal metaplasia is in doubt. Whether adenocarcinoma of the gastric cardia arises in intestinal metaplasia of the gastric cardia is also in doubt. We aim to evaluate the relationshi...

The intercellular junctions in the anterior myoepithelium and posterior pigmented epithelium of the rhesus monkey iris were examined using an ultrastructural tracer, conventional electron microscopy, and the freeze-fracture technique. Within the anterior myoepithelium the lateral cell margins were joined by puncta adhaerentia, desmosomes, and gap junctions. The distribution of the puncta adhaer...

The blood-air barrier in the lung consists of the alveolar epithelium, the underlying capillary endothelium, their basement membranes and the interstitial space between the cell layers. Little is known about the interactions between the alveolar and the blood compartment. The aim of the present study was to gain first insights into the possible interplay between these two neighbored cell layers...

Podocalyxin is a major membrane protein of the glomerular epithelium and is thought to be involved in maintenance of the architecture of the foot processes and filtration slits characteristic of this unique epithelium by virtue of its high negative charge. However, until now there has been no direct evidence for podocalyxin's function. Podocalyxin is a type 1 transmembrane sialoprotein with an ...

The gingiva surrounds each tooth and comprises the free gingival(gingival margin), attached gingiva and gingival sulcus. The attached gingiva is firmly attached to the underlying periosteum of the alveolar bone. It is continuous with the alveolar (or oral) mucosa and is demarcated from it by the muco-gingival junction. The free (or marginal) gingiva is that found coronal (ie towards the crown) ...