Between May 1986 and September 1990 a total of 43 patients with metastatic transitional cell carcinoma (TCC) of the urinary tract have been treated at our institution with combination chemotherapy (CMV) consisting of cisplatin 100mg m2 IV day 2; methotrexate 30mg m2 IV days 1,8; and vinblastine 4 mg m-2 IV days 1,8. Chemotherapy was recycled on day 22 and continued for a maximum of six cycles i...