DBSy, domain based security, information security, information assurance, commercial ICT services management, ITIL, ITSM, COBIT, BS 15000 DBSy (Domain Based Security) is a set of notations and techniques developed by QinetiQ specifically for the UK MoD, a large distributed organisation. DBSy provides a way of describing and assessing businessdriven information security requirements for network ...

Platelet activation is regulated by both positive and negative signals. G6B-b is an inhibitory platelet receptor with an immunoreceptor tyrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM). The molecular basis of inhibition by G6B-b is currently unknown but thought to involve the SH2 domain-containing tyrosine phosphatase SHP-1. Here we show that G6B-b...

Leukocyte mono-Ig-like receptor 3 (LMIR3) is an inhibitory receptor mainly expressed in myeloid cells. Coengagement of Fc epsilonRI and LMIR3 impaired cytokine production in bone marrow-derived mast cells (BMMCs) induced by Fc epsilonRI crosslinking alone. Mouse LMIR3 possesses five cytoplasmic tyrosine residues (Y241, Y276, Y289, Y303, Y325), among which Y241 and Y289 (Y241/289) or Y325 fit th...

The immune co-inhibitory receptors lymphocyte activation gene-3 (LAG3) and programmed cell death 1 (PD1) synergistically contribute to autoimmunity and tumor evasion. Here we demonstrate how they collaborate and interact to regulate T cell function. We first show that LAG3 and PD1 are co-expressed on both OVA-specific and non-specific T cells infiltrating murine ovarian tumors. Dual antibody bl...

A key aspect of Information Technology Service Management (ITSM) is the monitoring and evaluation of service performance – a task that is complicated by the presence of interrelationships among different service processes in a multiservice contract. While success in the service arrangement requires participant organizations’ knowledge about the nature of service dependency and their subsequent ...

religious tourism is one of the varieties of tourism that authorities in this filed , believe iran, due to its special cultural and religious capacities and geographical position , has an important role in developing religious tourism industry. one of the important factors that affects industry tourism, especially developing the religious one ,is the aerial transportation industry for the time ...

In this research, the efficiency of Recycled Glass Powder (RGP) is evaluated for improvement of polymer-modified bitumen and asphalt mixture performance. An extensive laboratory programm was undertaken for polymer-modified bitumen including Crumb Rubber (CR), Styrene Butadiene Styrene (SBS) and Styrene Butadiene Rubber (SBR). Rheological and mechanical proper...