Laura Costantin,1* Yuri Bozzi,2* Cristina Richichi,3 Alessandro Viegi,1 Flavia Antonucci,2 Marcella Funicello,3 Marco Gobbi,3 Tiziana Mennini,3 Ornella Rossetto,4 Cesare Montecucco,4 Lamberto Maffei,1,2 Annamaria Vezzani,3 and Matteo Caleo2 1Scuola Normale Superiore and 2Istituto di Neuroscienze, Consiglio Nazionale delle Ricerche, 56100 Pisa, Italy, 3Istituto di Ricerche Farmacologiche Mario N...

Background Severe/Non-controlled asthma (SNCA) is a crucial challenge for physicians and a socio-economic burden for National Health Services (NHS). In Italy more than 50% of costs for asthma (1-2% of total NHS expenditure) are due to SNCA and moreover, within the European Community Respiratory Health Survey, Italy was the country with the lowest % of ICS daily use (29%) and with the highest % ...

Pulmonology Unit, Department of Cardiology, Thoracic and Vascular Surgery and Critical Care Medicine, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy Infectious Diseases Unit, Department of Internal Medicine, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy Clinical Microbiology Laboratory, De...

1 Laboratory for Integrative Systems Medicine (LISM), Istituto di Informatica e Telematica, Consiglio Nazionale delle Ricerche, Pisa, Italy, 2 Laboratory for Integrative Systems Medicine (LISM), Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa, Italy, 3 Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy, 4 Department of Informatics,...

1 Milan Unit, Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Milan, Italy. 2 Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano (Mi) – Italy. 3 Department of Pediatrics Cancer Biology; 4 Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305. 5 Computational Research Unit, Center for Genomics Science@SEMM, Istituto I...

*Correspondence: [email protected] 1NEST, Scuola Normale Superiore and Istituto di Nanoscienze, CNR, Piazza dei Cavalieri, 7, Pisa, 56126, Italy Full list of author information is available at the end of the article Abstract We study the zero-temperature phase diagram of a one-dimensional array of QED cavities where, besides the single-photon hopping, an additional coupling between neighboring ...

In 1947, Ernst Chain moved from Oxford to Rome, hired as head of a new biochemistry department and of a penicillin production pilot plant in the Istituto Superiore di Sanità (Higher Health Institute). Here, he managed to make Rome one of the most important centres in the international network of antibiotic science. However, the development of the state-operated centre was not easy. Political an...

A Consensus Conference on Specific Learning Disorders has been promoted by the Italian National Institute of Health (Istituto Superiore di Sanità, ISS). The Consensus Conference consisted in a systematic review of the international literature addressing the issues of diagnosis, risk factors and prognosis, treatment, service delivery and organizational models for Specific Learning Disorders (rea...

Cord blood has proved itself, if correctly stored with rational criteria, an excellent source of stem cells for related and unrelated transplants. It has been recently proven that the factor which predicts the best the speed of engraftment in cord blood transplants in the dose of progenitor cells injected per kg of body weight of the recipient. This result has been obtained thanks to a careful ...

The Data Bank on Carcinogens (Banca Dati Cancerogeni, BDC) is a factual data bank, available on the Istituto Superiore di Sanità website, aimed at supporting the risk management decision making of central and local administrators. It can also represent a valuable tool for industry. The available information on carcinogenicity evaluations/classifications produced by European Union and by other i...