Lee, Wing-Kee, Malte Spielmann, Ulrich Bork, and Frank Thévenod. Cd -induced swelling-contraction dynamics in isolated kidney cortex mitochondria: role of Ca uniporter, K cycling, and protonmotive force. Am J Physiol Cell Physiol 289: C656–C664, 2005. First published April 20, 2005; doi:10.1152/ajpcell.00049.2005.—The nephrotoxic metal Cd causes mitochondrial damage and apoptosis of kidney prox...

Although the structure of the contractile unit in smooth muscle is poorly understood, some of the mechanical properties of the muscle suggest that a sliding-filament mechanism, similar to that in striated muscle, is also operative in smooth muscle. To test the applicability of this mechanism to smooth muscle function, we have constructed a mathematical model based on a hypothetical structure of...

The nephrotoxic metal Cd(2+) causes mitochondrial damage and apoptosis of kidney proximal tubule cells. A K(+) cycle involving a K(+) uniporter and a K(+)/H(+) exchanger in the inner mitochondrial membrane (IMM) is thought to contribute to the maintenance of the structural and functional integrity of mitochondria. In the present study, we have investigated the effect of Cd(2+) on K(+) cycling i...

Isolated papillary muscles have often been used in myocardial mechanical function studies. The objective of the present study was to compare the mechanical function of papillary muscle isolated from left ventricle between Wistar (W) and Wistar-Kyoto (WKY) rats of different ages (1, 3, 6 and 12 months), in order to examine whether there is a difference in intrinsic mechanical properties of muscl...

This paper presents the concept of muscle-driven locomotion for planar snake robots, which combines advantages both rigid and soft robotic approaches to enhance performance robot locomotion. For this purpose, two adjacent links are connected by a pair pneumatic artificial muscles wherein an alternate actuation these actuators causes rotational motion at connecting joints. The muscle-based actua...

At relatively low effort level tasks, surface electromyogram (sEMG) spectral parameters have demonstrated an inconsistent ability to monitor localized muscle fatigue and predict endurance capacity. The main purpose of this study was assess the potential time (Tend) prediction using logarithmic compared raw data. Ten healthy subjects performed five sets voluntary isotonic contractions until thei...