this review provides the basic principle and rational for roc analysis of rating and continuous diagnostic test results versus a gold standard. derived indexes of accuracy, in particular area under the curve (auc) has a meaningful interpretation for disease classification from healthy subjects. the methods of estimate of auc and its testing in single diagnostic test and also comparative studies...

An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm(3); total marginal dose, 24 Gy in 3 fractionations at the 50% isodose line. The patient has been free from seiz...

Introduction: Because of small size of the beamlets in IMRT, physical penumbra is one of the important dosimetric parameters and small changes in the penumbra will have a great impact on the results. The physical penumbra width is defined as the lateral distance between two specified isodose curves at a specified depth of phantom. In this study, after demonstrating the inconsi...

Background: Monte Carlo and experimental relative dose determination in a water phantom, due to a high dose rate (HDR) 192Ir source is presented for real energy spectrum and monochromatic at 356 keV. Materials and Methods: The dose distribution has been calculated around the 192Ir located in the center of 30 cm ×30 cm ×30 cm water phantom using MCNP4C code by Monte Carlo method. Relati...

Background: Due to the small size of the beamlets in IMRT (intensity modulated radiotherapy), physical penumbra is one of the important dosimetric parameters and small changes in the penumbra have a notable impact on the results. The physical penumbra width is defined as the lateral distance between two specified isodose curves at a specified depth of phantom. In this study, after demonstrating...