brain injury has a multiple pathophysiology for which there is no definite treatment. in this regard, tissue engineering is one of the probable strategies for repair of damaged tissue. but creating a proper model for testing the engineered products faced some difficulties, specially, when we want to evaluate the effects of a product on the volume of injury. the current brain injury methods coul...

traumatic brain injury (tbi) initiates a cascade of numerous pathophysiological events that evolve over time. despite the complexity of tbi, research aimed at therapy development has almost exclusively focused on single therapies, all of which have failed in multicenter clinical trials. a variety of brain insults, including traumatic brain injury, encephalitis, stroke, and status epilepticus (s...

introduction trauma is the most common cause of death in people aged 1–44 years and the third leading cause of death regardless of age. early diagnosis can shorten the time of emergency care and a quick transfer of patients to a treatment center. objective this study evaluates the mgap scoring system to predict mortality in trauma patients. materials and methods in this cross-sectional study, 5...

it was estimated that 3 million people suffered from spinal cord injury. unfortunately up to date, there are not any reliable clinical treatments for spinal cord injury and researches for treatments of sci have focused on medication, surgery, stem cell transplantation, molecular therapy and tissue engineering. also scientists are trying to use a combination of stem cells and nanotechnology scie...

there are occasional reports of using the appendix to replace sections of the ureters, and to our knowledge, only a couple of them were in the left side. we used the appendix as a ureteral substitute in two cases in technically difficult parts, the upper left ureter and the first part of the right ureter. follow-ups of8 years and 6 months in right and left side cases, respectively, are impressi...

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background: burn injuries and their complications are still considered major threats to society’s health standards. the aim of this study was to describe the epidemiological profile, outcome, and factors associated with children’s burn injuries in shahroud (northeastern iran). methods: this cross-sectional study was performed over a three-year period (2013–2015) on children 12 years and under w...

minor trauma to the head is common in childhood and does not require any medical or surgical treatment. nevertheless, head injury in infancy and childhood is the single most common cause of death and permanent disability. measurable deficits occur even after mild to moderate head injury but are markedly greater after severe injury. they include impaired cognition, motor impairments, disruption ...

introduction: cisplatin is used as a chemotherapeutic agent for the treatment of human ovarian and testicular cancers. this study was designed to investigate the protective role of taurine against cisplatin-induced kidney injury. methods: male wistar rats were divided into 4 groups (n=8) (1) saline-treated group (2) cisplatin-treated group (10 mg/kg, i.p.), (3) group that received taurine (200 ...

background: unexplained infertility is still a challenging issue as to its causes, appropriate management and treatment. evidence implicates early embryopathy or implantation failure as likely causes. objective: this study aims to investigate the effect of local endometrial injury on pregnancy rate in selected unexplained infertile patients. materials and methods: this was a randomized clinical...