The history of kidney and urologic disorders dates back to the dawn of civilization. Throughout history of medicine, urine, the first bodily fluid to be examined, has continuously been studied as a means of understanding inner bodily function. The purpose of this review was to appraise the contributions of the ancient Iranian physician pioneers in the field of kidney and urological disorders, a...

BACKGROUND Patient empowerment can enhance the outcomes of care such as metabolic control as well as quality of their life. This study evaluates the Iranian version for development of a valid and reliable diabetes empowerment scale. METHODS Validity and reliability of Iranian version of Diabetes Empowerment Scale (DES-LF) were measured through a cross-sectional study. DES-LF was evaluated thr...

The role of the major histocompatibility complex (MHC) in the immune response makes it an attractive candidate gene for associations with disease resistance and susceptibility. This study describes genetic variability in the BoLA-DRB3 in Iranian buffaloes. Heminested PCR-RFLP method was used to identify the frequency of BoLA-DRB3 alleles. The BoLA-DRB3 locus is highly polymorphic in the study h...

Cigarette smoking continues to be a major public health problem that specifically affects the adolescent population. The prevalence of cigarette smoking among Iranian adolescents has been reported between 2.5 to 17.0% (1). Such a broad range is primarily due to the variety of the definition of “being a smoker”, the age difference of the samples under study and the location where such studies ha...

Multidrug resistance (MDR) is a main cause of failure in the chemotherapeutic treatment of malignant disorders. One of the well-known genes responsible for drug resistance encodes the multidrug resistance- associated protein (MRP1). The association of MRP1 with clinical drug resistance has not systematically been investigated in Iranian pediatric leukemia patients. We therefore applied real-tim...

Background: Many cardiovascular diseases may require lifelong anticoagulation therapy. Warfarin is the most prescribed medication in this regard, however, it has serious side effects. Recently the new issue regarding to warfarin dosing is considered in which some single nucleotide polymorphisms (SNPs) affecting cytochrome P450 system can impact on warfarin metabolism and dosing. Methods: 230 c...

The major difference between Iranian traditional medicine and allopathic medicine is in the application  of  evidence  and  documents.  In  this  study,  criteria  for  evidence-based  practice  in  Iranian traditional medicine and its rules of practice were studied. The experts' views were investigated through in- depth, semi-structured interviews and the results were categorized into four mai...

URINARY INCONTINENCE MANAGEMENT: A SYSTEMATIC REVIEW AND META-ANALYSIS Sakineh Hajebrahimi, Alireza Mahboub-Ahari, Neda Kabiri, Fariba Pashazadeh. Department of Urology, Iranian Evidence-Based Medicine Center of Excellence(RCEBM), Tabriz University of Medical Sciences, Tabriz, Iran; Iranian Center of Excellence in Health Management, Tabriz University of Medical Sciences, Tabriz, Iran; Ph.D. Stu...

Journal of Research in Medical Sciences | May 2014 | 385 Observation of constant increase of self-citation rate by Iranian scholars in all fi elds shows that self-citation plays an important role in scientifi c communication even in the fi eld of medicine. Base on Ghane’s study[8] the rate of journal self-citation among Iranian medical journals is about 61.5% and with reared to the Iranian auth...