BACKGROUND Kashin-Beck disease is an osteoarthropathy endemic in selenium- and iodine-deficient areas around Lhasa, Tibet. OBJECTIVE We assessed the efficacy of selenium supplementation on disease progression. DESIGN A double-blind, randomized controlled trial of selenium supplementation was carried out in 324 children aged 5-15 y who had Kashin-Beck disease. Two hundred eighty children rec...

use of a mixture of sulphanilamide and iodized oil, and this was used later by Houghton and Ramsay (1951). Though this mixture largely avoided the difficulty of retention in the alveoli, it was extremely viscous and rather difficult to expel from the syringe. The introduction of propyliodone ("dionosil") has rendered the use of such mixtures unnecessary, since any propyliodone which does reach ...

The importance of micronutrients in human development has received increasing attention both in medical science and in economic policymaking. Iodine de…ciency is one of the most discussed issues related to micronutrients in the context of less developed countries. Given that systematic evidence of the e¤ectiveness of iodine supplementation in developing countries is still lacking, my study eval...

BACKGROUND Iodine deficiency is severe public health problem in Ethiopia. Although urinary iodine excretion level (UIE) is a better indicator for IDD the goitre rate is commonly used to mark the public health significance. The range of ill effect of IDD is however beyond goitre in Ethiopia. In this study the prevalence of goitre and its association with reproductive failure, and the knowledge o...

OBJECTIVE To evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with N-Butyl Cyanoacrylate (NBCA) for nonvariceal upper gastrointestinal bleeding. MATERIALS AND METHODS Between March 1999 and December 2002, TAE for nonvariceal upper gastrointestinal bleeding was performed in 93 patients. The endoscopic approach had failed or was discarded as an approach for...

OBJECTIVE To evaluate the effectiveness of universal salt iodization (USI) for the control of IDD in Hebei province since it was implemented in 1995, identify the problems currently encountered in the implementation of USI and provide practical proposals for addressing these problems. METHODS Probability proportionate to size sampling (PPS) was employed in the surveillance of IDD, for which a...

Food fortification is a cost-effective approach to prevent and control of micronutrient deficiencies in India. A cross-sectional survey of children 0-35 months of age residing in the catchment areas of anganwadi centers in the state of Telangana was conducted to assess the coverage of adequately iodized salt and the potential for rice fortification. Salt samples were collected and tested for io...

While traditionally associated with cretinism and goiter, iodine deficiency has broad effects on central nervous system development that can occur in the absence of either condition. Any maternal iodine deficiency results in a range of intellectual, motor, and hearing deficits in offspring. This loss in intellectual capacity limits educational achievement of populations and the economic prowess...

BACKGROUND In Rajasthan, an Indian State with significant salt production, the sale of non-iodized salt for human consumption was banned in 1992. This study explored the relationships between the use of iodized salt in Rajasthan and the iodine status of children and pregnant women living in the area. METHODS In a State-wide survey, 30 clusters were selected proportionate-to-population-size an...