Intracranial haemorrhage is commonly found at necropsy in association with hyaline membrane disease. The bleeding usually occurs in the subarachnoid or intraventricular sites (Hutchison, Kerr, Douglas, Inall, and Crosbie, 1964), but its cause is as yet poorly established. Cerebral haemorrhage unrelated to hyaline membrane disease frequently occurs in premature infants (Craig, 1938), and anoxia ...

Fifty infants who weighed 1250 g or less at birth were studied with serial real time cerebral ultrasound to evaluate the temporal relation of various perinatal factors to the onset and progression of periventricular haemorrhage (PVH). The significant antecedents of PVH were severe bruising at birth, low birthweight, short gestation, ratio of arterial oxygen pressure (PaO2) to fractional inspire...

BACKGROUND Despite the widespread use of antenatal corticosteroids to prevent respiratory distress syndrome in preterm infants, there is currently no consensus as to the type of corticosteroid to use; nor the dose, frequency or timing of use or the route of administration. OBJECTIVES To assess the effects of different corticosteroid regimens for women at risk of preterm birth. SEARCH STRATE...

www.thelancet.com Vol 382 August 3, 2013 377 In The Lancet, David Mendelow and colleagues report the results of their second randomised STICH (STICH II) trial of early surgery compared with initial conservative treatment for patients with superfi cial lobar intracerebral haemorrhage. They included 597 patients from 78 centres in 27 countries; 589 of 597 patients were available for follow-up at ...

A mother, newly found to be positive for HIV, delivered her first baby at 25 weeks gestation. The infant initially did well in spite of a symptomatic patent duct and a severe intraventricular haemorrhage, but became severely unwell needing further respiratory support on day 18. Acid fast bacilli were found in endotracheal secretions. After the baby's death, the bacilli were confirmed to be Myco...

Serial computed tomographic scans in 39 closed head injury patients were measured by planimetry. The ventricle-brain ratio was computed, and the lateral ventricles were considered to be enlarged or normal based on measurements from a control group. Delayed ventricular enlargement was common after head injury producing low Glasgow Coma Scale scores and prolonged coma, whereas subarachnoid/intrav...