Advances in neuropsychosis have concluded that addiction is a chronically relapsing brain disorder. Cue-, drug-and (or) stressprimed reinstatement play important parts on the development of drug abuse. Stress is a key factor in the acquisition and persistence to illicit drugs and psychostimulants such as cocaine, heroin, ketamine, alcohol and nicotine. When the access to the drug is prevented, ...

Forty-six of 139 first visit patients who attended the Drug Advisory and Treatment Centre in the Charitable infirmary with a problem of intravenous drug abuse, between May 1st 1979 and December 31st 1979, had liver biopsies carried out. Eight of these patients had chronic active hepatitis; these and 4 other abusers with chronic active, hepatitis who were attending the Department of Gastroentero...

This report illustrates a case of a 42-year-old male with a history of intravenous drug abuse who presented with septic shock. Diagnostic studies, including a transthoracic echocardiogram, chest computed tomography angiography, transesophageal echocardiogram, and blood cultures ultimately revealed Serratia marcescens pulmonic valve infective endocarditis that was treated with intravenous antibi...

Background: Earlier reports of cocaine-associated cerebral vasculitis have been based primarily on angiographic findings without pathological verification. Case Description: We present a case of acute encephalopathy following intravenous and intranasal administration of cocaine. Brain biopsy revealed vascular changes involving primarily small arteries. Findings included lymphocytic infiltration...

background: infections include soft tissue infections are notable reason for hospital admission among idus, owing to unsterile injection techniques and equipment, contamination of drugs with organisms, and poor hygiene. in present case report a patient with profound limb infection is introduced. case: a 32 years old man was transferred to the emergency department. he was idu with iranian for 3 ...

during a cross-sectional study, patients who were admitted to the orthopedic department of the urmia university of medical sciences were asked about opium/opioid abuse. demographic characteristics, the pattern of consumption, the substance, the duration of the use, the duration of hospital stay and the cause of their injuries were recorded. among 2,867 patients, 74 (2.5%) patients (71 men and 3...

provided the original work is properly cited. CC A 50-year-old man awoke suddenly at 4:30 a.m., stood on his bed, and cried out, “I told you I could not sleep all night!” Thereafter, he tried to find an anesthesiologist to infuse him with the surgical anesthetic propofol because he was convinced it was the only cure for his insomnia. Finally, he died, 65 days later, from an overdose of propofol...

BACKGROUND Opioid analgesics can be abused by crushing followed by solubilization and intravenous injection to attain rapid absorption. Morphine sulfate and naltrexone hydrochloride extended release capsules (EMBEDA, MS-sNT), indicated for management of chronic, moderate to severe pain, contain pellets of morphine sulfate with a sequestered naltrexone core. Should product tampering by crushing ...

background : drug injection is one of the most significant risk factors for viral hepatitis and human immunodeficiency virus (hiv) infection. the present study was performed to evaluate the frequency of hepatitis b (hbv) and hiv infection in idus and to identify the risk factors of these infections in this group in a central city of iran, shahre-kord. methods : this study was conducted in 2004 ...