Local anesthetic toxicity remains a clinical concern when performing regional anesthesia. Because signs and symptoms of toxicity may not appear for 20 to 30 minutes after administration of local anesthetic, vigilance is crucial. When signs and symptoms of local anesthetic toxicity appear, traditional standards mandate resuscitative measures, including maintenance of oxygenation, elimination of ...

Background & Aims: Abuse of topical anesthetic drops causes serious ocular complications. Obtaining information about the prevalence of anesthetic drops abuse among high risk groups specially welders is necessary for taking appropriate strategies for prevention. The present study aimed at determining the prevalence of anesthetic drops abuse among welders in Kerman. Methods: In this cross-se...

DEXMEDETOMIDINE is a highly selective 2 adrenoceptor agonist that has sedative and analgesic properties with associated reduction in opioid and anesthetic requirements. One significant advantage of dexmedetomidine is that in the clinical dose range there is no respiratory depression. The agonistic action on the 2 adrenoceptors in the sympathetic ganglia modulates the release of catecholamines, ...

BACKGROUND Multiple comorbidity measures have been developed for risk-adjustment in studies using administrative data, but it is unclear which measure is optimal for specific outcomes and if the measures are equally valid in different populations. This research examined the predictive performance of five comorbidity measures in three population-based cohorts. METHODS Administrative data from ...

443 August 2013 I NFANTS with hypotonia of unknown etiology pose a unique challenge as many of the potential diagnoses have major, often conflicting, anesthetic management implications. The differential diagnosis of hypotonia is long and includes possibilities such as Duchenne muscular dystrophy, central core disease, and multiminicore disease. Intravenous anesthetic techniques are recommended ...

T he bronchoscope is often used in the diagnosis of pulmonary diseases and there is no disagreement regarding the justification for this diagnostic proce(lure. Opinions are somewhat divided as to the best method of ensuring anesthesia with adequate ventilation and oxygenation during the procedure. The purpose of this article is to try to elucidate this prol)lem and bring forward the most recent...

The question of how structurally and pharmacologically diverse general anesthetics disrupt consciousness has persisted since the nineteenth century. There has traditionally been a significant focus on "bottom-up" mechanisms of anesthetic action, in terms of sensory processing, arousal systems, and structural scales. However, recent evidence suggests that the neural mechanisms of anesthetic-indu...

Computable general equilibrium (CGE) modeling has provided a number of important insights about the interplay between environmental tax policy and the pre-existing tax system. In this paper, we emphasize that a labor market policy of recycling tax revenues from an environmental tax to lower employers’ non-wage labor cost depends on how the costs of labor are modeled. We propose an approach, whi...

AIMS For children with stable asthma, to test non-inferiority of care provided by a hospital-based specialised asthma nurse versus a general practitioner (GP) or paediatrician. METHODS Randomised controlled trial evaluating standard care by a GP, paediatrician or an asthma nurse, with two-year follow-up. RESULTS 107 children were recruited, 45 from general practice and 62 from hospital. Aft...