BACKGROUND AND PURPOSE Despite the successful use of a ketogenic diet in pediatric epilepsy, its application in adults has been limited. The aim of this meta-analysis was to summarize the findings of relevant published studies in order to identify the efficacy of and compliance with a ketogenic diet and its main subtypes (i.e., classic ketogenic diet and modified Atkins diet) in adults with int...

Epilepsy is one of the oldest and commonest neurological diseases and presently considered a common global problem. The prevalence of epilepsy is estimated to be one in hundred in the general population with a distinctly higher degree of affliction in underdeveloped and developing countries. This is further compounded by more than one-third of all epilepsy cases not responding satisfactorily to...

how to cite this article: taghdiri mm, bakhshandeh bali mk, karimzadeh p, ashrafi mr, tonekaboni sh, ghofrani m. comparative efficacy of zonisamide and pregabalin as an adjunctive therapy in children with refractory epilepsy. iran j child neurol. 2015 winter;9(1):49-55. abstract objective approximately one third of epileptic children are resistant to anticonvulsant drugs. this study evaluates t...

The ketogenic diet has traditionally been considered an anticonvulsant therapy of last resort, despite excellent efficacy and limited side effects. We hypothesized that the ketogenic diet would have similar results in patients with new-onset epilepsy. A retrospective study was conducted of patients started on the ketogenic diet since 1994. Thirteen of 460 (2.8%) patients were started on the ket...

This study presents the results of a rehabilitation program in a spastic hemiparetic subject who had undergone hemispherectomy because of SturgeWeber syndrome and intractable epilepsy. Sturge-Weber syndrome includes unilateral cerebral cortical angiomatosis, which often leads to progressive cerebral dysfunction and epileptic seizures that are medically difficult to control. A three-year-old gir...

OBJECTIVES To study the outcome of disconnective epilepsy surgery for intractable hemispheric and sub-hemispheric pediatric epilepsy. METHODS A retrospective analysis of the epilepsy surgery database was done in all children (age <18 years) who underwent a peri-insular hemispherotomy (PIH) or a peri-insular posterior quadrantectomy (PIPQ) from April 2000 to March 2011. All patients underwent ...