Background : Carotid intima-media thickness (CIMT) has been proposed as a surrogate marker to identify diabetic patients at higher risk for CAD. Oxidative stress has been postulated to be involved in the development of atherosclerosis. Objective: The present study was to evaluate the effect of taurine on serum lipids, lipid peroxidation and RBC antioxidant status and vessel changes in type 2dia...

OBJECTIVE Advanced glycation end-products are considered to be markers of oxidative stress and to be involved in the atherosclerotic process. We investigated skin autofluorescence, which reflected advanced glycation end-product accumulation, in recently preeclamptic women and its relationship with intima-media thickness, which is a marker of atherosclerosis. STUDY DESIGN Skin autofluorescence...

Psoriasis is a chronic inflammatory skin disorder associated with increased cardiovascular risk. Aim of this work was to evaluate the association between psoriasis and chosen cardiovascular risk factors, echocardiographic parameters, and carotid intima-media thickness. A total of 50 patients with psoriasis and 50 controls were enrolled in the study. Psoriasis area severity index was calculated ...

We compared the endothelial function and vascular wall characteristics of 11 children with tetralogy of Fallot (TOF) (age 13 +/- 3 years) with the characteristics of 17 age-matched peers (12 +/- 2 years). Echocardiographic Doppler measurements were performed under standardized conditions to assess (1) the carotid and femoral artery diameter and intima-media thickness, (2) brachial artery endoth...

BACKGROUND AND PURPOSE Parity is associated with the risk of clinical cardiovascular events and the severity of preclinical atherosclerosis in older subjects. We sought to determine whether childbearing is associated with concurrent changes in cardiovascular risk factors and the progression of carotid intima-media thickness. METHODS We examined the association between the number of children b...

OBJECTIVE To quantify the direct and indirect effects of fetal life, childhood, and adult life on risk of cardiovascular disease at age 49-51 years. DESIGN Follow up study of the "Newcastle thousand families" birth cohort established in 1947. PARTICIPANTS 154 men and 193 women who completed a health and lifestyle questionnaire and attended for clinical examination between October 1996 and D...

OBJECTIVE Obesity is associated with cardiovascular risk and a low-grade inflammatory state in both blood and adipose tissue (AT). Whether inflammation contributes to vascular alteration remains an open question. To test this hypothesis, we measured arterial intima-media thickness (IMT), which reflects subclinical atherosclerosis, in severely obese subjects and explored associations with system...

Bone mineral density (BMD) has been suggested to be associated with atherosclerosis. In the present study, we evaluated the association between lumbar BMD and the segments of carotid intima-media thickness (CIMT), a surrogate marker of subclinical atherosclerosis, in Korean adults, with consideration of sex and menopause status. Among 1,679 Korean adults who enrolled in a Healthy Twin Study, 72...

Keywords: Cardiovascular risk factors Carotid intima-media thickness Kidney transplant recipients South Africa. Background: Cardiovascular diseases (CVD) are more common in kidney transplant recipients (KTRs) than in the general population. Carotid intima-media thickness (cIMT) is a marker of atherosclerosis in the general and transplant populations. We determined the prevalence and predictors ...

BACKGROUND AND PURPOSE Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis. METHODS Subjects were 244 adults 30 to 55 years of age and free of clinic...