Human small intestine epithelial cells (enterocytes) provide the first site for cytochrome P-450 (CYP)-catalyzed metabolism of orally ingested xenobiotics. The CYP composition of enterocytes could thus affect the potential toxicity or therapeutic efficacy of xenobiotics by modifying systemic uptake. We have characterized human enterocyte CYP composition to enable assessment of its functional ro...

Acute normovolemic hemodilution (ANH) compromizes intestinal microcirculatory oxygenation; however, the underlying mechanisms are incompletely understood. We hypothesized that contributors herein include redistribution of oxygen away from the intestines and shunting of oxygen within the intestines. The latter may be due to the impaired ability of erythrocytes to off-load oxygen within the micro...

Gastroschisis is a prenatal abdominal wall defect in which the intestines exit body from hole abdomen, usually located to right of umbilical cord. Incidence as described literature 2-5/1000 live births, and overall survival 90% [1].

BACKGROUND/AIMS Several motility disorders are associated with disruption of interstitial cells of Cajal (ICC), which provide important functions, such as pacemaker activity, mediation of neural inputs and responses to stretch in the gastrointestinal (GI) tract. Restoration of ICC networks may be therapeutic for GI motor disorders. Recent reports have suggested that Kit(+) cells can be restored...

The sulfate uptake and accumulation in mouse digestive organs were studied by light microscopic radioautography. Two litters of normal ddY mice 30 days after birth, each consisting of 3 animals, were studied. One litter of animals were sacrificed 30 min after the intraperitoneal injections with phosphate buffered Na2(35)SO4, and the other litter animals were sacrificed 12 hr after the injection...

This study investigated the effects of glycinin on the growth, intestinal oxidative status, tight junction components, cytokines and apoptosis signalling factors of fish. The results showed that an 80 g/kg diet of glycinin exposure for 42 d caused poor growth performance and depressed intestinal growth and function of juvenile Jian carp (Cyprinus carpio var. Jian). Meanwhile, dietary glycinin e...

The objective of this study was to investigate the size of the small and large intestine in postnatal development of Mus musculus mice. The gut was obtained from 2-, 4-, 6-, and 12-week-old animals. The morphometric analysis was performed at microscopic level. Measurements and calculations included dimensions of villi (height, diameter) and their number per 1 mm(2) surface area in the proximal,...

A study was conducted to measure the extent of DM disappearance and mineral release from six forage species within the rumen, abomasum and intestines of the adult bovine using the mobile bag technique. Three nonlactating Holstein cows, fitted with ruminal and duodenal cannulas, were given ad libitum access to alfalfa hay. One gram (DM) of alfalfa, rhizoma peanut, dwarf elephantgrass, bahiagrass...

The study was conducted to explore the anti-heat stress efficacy of anti-heat stress prescription (AHSP) and to test its safety. Kunming (KM) mice were randomly divided into the control group, the AHSP group, the heat stress (HS) group, and the (AHSP+HS) group. Following 8 days i.g. administration, the HS group and the (AHSP+HS) group were treated with heat stress to the rectal temperature reac...

The study aimed to evaluate the effect of Thepax and BioBoost as food additives on microorganisms in intestines fish. From March 4 October 22, total number common carp was 900 fish with an average weight 163.41 ±10.16 g a density 100 fish/cage; three replicates were used for each treatment. fed times daily. included T1(0%additive), T2(1g/kgThepax)and T3 (1 g/kgBioBoost). highest final value is ...