The present study deals with the elastic analysis of concave thickness rotating disks made of functionally graded materials (FGMs).The analysis is carried out using element based gradation of material properties in radial direction over the discretized domain. The resulting deformation and stresses are evaluated for free-free boundary condition and the effect of grading index on the deformation...

Many researches point out that intervertebral pressure and transformation are key parameters for evaluating intervertebral disc degeneration. Aiming at avoiding the damage caused by direct and indirect measuring methods, this research proposes a cylindroid hypothesis and measuring method, which can monitor the strain condition of the intervertebral disc in vivo and real-time without being damaged.

Although human intervertebral disc degeneration can lead to several spinal diseases, its pathogenesis remains unclear. This study aimed to create a new histological classification applicable to an in vivo mouse intervertebral disc degeneration model induced by needle puncture. One hundred six mice were operated and the L4/5 intervertebral disc was punctured with a 35- or 33-gauge needle. Micro-...

Pains which seem predominantly to affect the muscles are extremely common and many hypotheses regarding their genesis have been developed, but most of them have lost support in time. The concept of "fibrositis", so popular 20 years ago, is now almost universally suspect, and few would claim that any sound basis for it has been discovered. But the destruction of a hypothesis, such as "fibrositis...

PURPOSE Our goal was to compare contrast enhancement of recurrent herniated disk fragments and scar after intravenous injection of a new high-molecular-weight contrast medium, Gadomer 17 (gadomer), with that after injection of a low-molecular-weight contrast medium, (gadopentetate dimeglumine). METHODS Recurrent herniated disks were modeled in dogs by placing a fragment of intervertebral disk...

INTRODUCTION: Bulging of the intervertebral discs during normal motion of the spine has been proposed as a potential cause of pain through either compression of the spinal cord or impingement of exiting neural elements. Although past studies have characterized both normal and stenotic dimensions of the spinal canal and intervertebral foramen, no previous study has described the amount of disc o...

Degenerative disk disease is an accelerating cascade of tissue degeneration in the intervertebral disk. A harsh catabolic environment perpetuates the degeneration of the intervertebral disk. Tissue engineering-based techniques offer effective treatment to slow the progression of degenerative disk disease and regenerate intervertebral disk tissue. The purpose of this study was to assess the effi...

Intervertebral disc degeneration is a primary cause of low back pain and has a high societal cost. The pathological mechanism by which the intervertebral disc degenerates is largely unknown. Cell-based therapy especially using bone marrow mesenchymal stem cells as seeds for transplantation, although still in its infancy, is proving to be a promising, realistic approach to intervertebral disc re...

INTRODUCTION Varied definitions of disc pathology exist in the literature. Magnetic Resonance Imaging (MRI) classification systems incorporate several qualitative features including disc appearance, the distinction between the nucleus and the annulus, signal intensity and intervertebral disc height. The lack of a continuous measure has made it difficult to sensitively examine degenerative disc ...