BACKGROUND The neuronal isoform of nitric oxide synthase (NOS-1) may be an important regulator of cardiac contractility by modifying calcium release and uptake from sarcoplasmic reticulum. Our working hypothesis was that NOS-1 modulates cardiomyocyte contractility more markedly in rat lines with low versus high congenital aerobic fitness. METHODS AND RESULTS Rats performed high-intensity inte...

introduction: effects of exercise on different body systems, especially cardiovascular and musculoskeletal systems are evidenced. there is a dynamic homeostatic balance between coagulation and fibrinolysis in normal circulation. effect of exercise and training on this homeostatic balance has been studied extensively but there are a few studies with regards to analysis of the effects of training...

PURPOSE Runners use uphill running as a movement-specific form of resistance training to enhance performance. However, the optimal parameters for prescribing intervals are unknown. The authors adopted a dose-response design to investigate the effects of various uphill interval-training programs on physiological and performance measures. METHODS Twenty well-trained runners performed an increme...

patients and methods twenty-two young men (age = 23.34 ± 2.56 years, weight = 72.47 ± 12.01 kg, and height = 174.10 ± 5.75 cm) were recruited and randomly assigned into control (n = 10) and hiit (n = 12) groups. echocardiography was used to evaluate left ventricular mass (lvm), end-systolic volume (esv), end-diastolic volume (edv), interventricular septal wall thickness (ivswt), stroke volume, ...

The purpose of the study was to examine the effects of sprint interval training (SIT) and moderate-intensity continuous cycle training (MICT), with equal estimated energy expenditure during training on body composition and aerobic capacity. Body composition measured via dual-energy X-ray absorptiometry and aerobic capacity were assessed following 6 weeks of training in previously inactive overw...

Purpose. The aim of this study was to compare the effects of high-intensity interval training (INTERVAL) and moderate-intensity continuous training (CONTINUOUS) on aerobic capacity in cardiac patients. Methods. A meta-analysis identified by searching the PubMed, Cochrane Library, EMBASE, and Web of Science databases from inception through December 2016 compared the effects of INTERVAL and CONTI...

Performance in intense exercise events, such as Olympic rowing, swimming, kayak, track running and track cycling events, involves energy contribution from aerobic and anaerobic sources. As aerobic energy supply dominates the total energy requirements after ∼75s of near maximal effort, and has the greatest potential for improvement with training, the majority of training for these events is gene...

BACKGROUND Training of young Thoroughbred horses must balance development of cardiopulmonary function and aerobic capacity with loading of the musculoskeletal system that can potentially cause structural damage and/or lameness. High-speed equine treadmills are sometimes used to supplement exercise on a track in the training of young Thoroughbreds because the horse can run at high speeds but wit...

leptin is a hormone, which is secreted from fat tissue, has an important role to set cell metabolism and energy balance. the present study aims at the effect of twelve weeks high intensity interval training (hiit) on leptin level and obesity dependent factors among female students suffering overweight. in this semi-experimental study, twenty four students with bmi of 25-30 kg/m2 were selected p...