An environmentally benign RP-HPLC approach for rapid analysis of glibenclamide in pure form, developed nanoemulsion and commercial tablets was developed and validated in present investigation. The green chromatographic identification was performed on Lichrosphere 250 X 4.0 mm RP C8 column having a 5µm packing as a stationary phase using a combination of ethanol: methanol (50:50 % v/v) as a mobi...

An environmentally benign RP-HPLC approach for rapid analysis of glibenclamide in pure form, developed nanoemulsion and commercial tablets was developed and validated in present investigation. The green chromatographic identification was performed on Lichrosphere 250 X 4.0 mm RP C8 column having a 5µm packing as a stationary phase using a combination of ethanol: methanol (50:50 % v/v) as a mobi...

Nowadays harmonization of sanitary and hygienic standards of environmental quality with international standards is crucial part of integration of Russia into the international community. Harmonization of Russian and international ambient air quality standards may be realized by risk-based standards development. In this paper approaches to risk-based standards development and examples of these a...

This Comment argues that the parties to the International Conference on Harmonization of Technical Requirements for Regulation of Pharmaceutical Drugs (ITCH) should adopt more specific guidelines for pediatric research than those included in its Good Clinical Practice Guidelines (ICH GCP), and analyzes their attempt to do so in the Draft Guideline on Pediatric Trials. Part I of this Comment out...

The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) was established in 1990. Since then, representatives of the regulatory authorities and pharmaceutical industries from Europe, Japan and the US have held discussions on issues about the technical requirements for safety, efficacy quality, and multidisciplinary areas. Th...

This paper aims at analyzing the content of the conferences contained in the ISCA Archive over the past 25 years. It follows a similar exercise that has been conducted within the Computational Linguistics community over 50 years of existence at the ACL conference in 2012, and a survey on the IEEE ICASSP conference series from 1976 to 1990, which served in the launching of the ESCA Eurospeech co...

1. Abstract: A new, simple, precise, accurate and selective high performance thin-layer chromatographic (HPTLC) method has been developed and validated for the simultaneous determination of Tolperisone hydrochloride and Diclofenac sodium in a tablet dosage form. Chromatographicseparation was carried out on Merck TLC aluminium sheets of silica gel 60F254 using Toluene: Ethyl acetate: Methanol (4...

BACKGROUND Alpinia galanga (L.) Willd. commonly called as Rasna, Greater galangal or Kulinjan is a medicinally important rhizome used in Indian traditional system of medicine to cure a number of ailments. A. galanga is the main source of a galangin -a medicinally important flavanol which has a number of pharmacological properties viz. anti-mutagenic, and anti-inflammatory. Due to the high deman...

A simple, precise, accurate stability-indicating gradient reverse phase ultra-performance liquid chromatographic (RP-UPLC) method was developed for the quantitative estimation of purity of Telmisartan drug substance and drug products in bulk samples and pharmaceutical dosage forms in the presence of its degradation products and impurities. The present method was developed using Waters Aquity BE...