Intermittent claudication in peripheral arterial disease limits exercise capacity. Rehabilitation can produce an improvement in absolute walking distance. Very often changes in skeletal muscle, rather than changes in blood flow, are responsible for the improved exercise capacity. We studied 8 patients with intermittent claudication (Fontaine 2 class) that underwent a 4week treadmill mild-modera...

Here we summarize topics covered in an SFN symposium that considered how and why exercise and energy intake affect neuroplasticity and, conversely, how the brain regulates peripheral energy metabolism. This article is not a comprehensive review of the subject, but rather a view of how the authors' findings fit into a broader context. Emerging findings elucidate cellular and molecular mechanisms...

Twenty-one patients (19 men and two women) with disabling exercise-related leg pain attended a physiotherapy department on one afternoon each week for an exercise training programme lasting one month. The clinical diagnosis of intermittent claudication and localisation of the atherosclerotic occlusions were confirmed in all but one case by pulse volume recordings and segmental Doppler systolic ...

Background—This prospective, randomized, controlled clinical trial compared changes in exercise performance and daily ambulatory activity in peripheral artery disease patients with intermittent claudication after a home-based exercise program, a supervised exercise program, and usual-care control. Methods and Results—Of the 119 patients randomized, 29 completed home-based exercise, 33 completed...

Effects of continuous and intermittent trainings on exercise-induced hematuria and proteinuria in untrained adult females Sir, Exercise can induce temporary proteinuria (18–100%) and hematuria (20–100%), which usually resolve within 24–48 h [1]. Proteinuria is mainly influenced by exercise intensity rather than duration, while hematuria depends on both duration and intensity [2, 3]. Most invest...

Recent literature suggests that ergogenic substances may play a beneficial role in intermittent exercise. Maltodextrin supplementation has been investigated soccer players, but few studies have reported. The aim of this study was to evaluate the effect 6% maltodextrin on capillary lactate players. carried out during training, which characterised by intense activity (90 min). Participants (n = 2...

Background It has been suggested that carbohydrate-protein based multi-ingredient supplements may attenuate exercise induced muscle damage (EIMD) and immunosuppression. This study investigates the effects of a commercially available carbohydrate-protein supplement (MTN) enriched with L-glutamine, L-carnitine-L-tartrate compared to carbohydrate alone (CHO) or placebo (PL), on sprint performance,...

Purpose: To investigate the role of sodium-hydrogen exchanger-1 (NHE-1) and exercise training on intermittent hypoxia-induced cardiac fibrosis in obstructive sleep apnea (OSA), using an animal model mimicking the intermittent hypoxia of OSA. Methods: Eight-week-old male Sprague-Dawley rats were randomly assigned to control (CON), intermittent hypoxia (IH), exercise (EXE), or IH combined with ex...

We assessed the cardiorespiratory responses and exercise tolerance during 12 week training (intermittent vs. continuous) in obese children. Twenty nine obese adolescent were randomly allocated into either the IT or CT group. The CT group performed a 30 to 40 minute continuous exercises a 60% to 70 % of vVO2max. IT group was instructed to run for 2 min interspersed with recovery periods of one m...

OBJECTIVES We sought to compare standard lower extremity vascular laboratory treadmill exercise with the office-based active pedal plantarflexion technique. BACKGROUND Intermittent claudication is relatively common in elderly patients and is an important predictor of cardiovascular morbidity and mortality. Noninvasive testing using resting and posttreadmill exercise ankle:brachial systolic bl...