An investigation of a series of seven angular "V" shaped NPIs (1-7) is presented. The effect of substitution of these structurally similar NPIs on their photophysical properties in the solution-state and the solid-state is presented and discussed in light of experimental and computational findings. Compounds 1-7 show negligible to intensely strong emission yields in their solid-state depending ...

In this paper, the problem of control and stabilization of a bilateral tele-surgery roboticsystem in interaction with an active soft tissue is considered. To the best of the authors’ knowledge, theprevious works did not consider a realistic model for a moving soft tissue like heart tissue in beating heartsurgery. Here, a new model is proposed to indicate significant characteristics of a moving ...

background: patients with primary sjögren’s syndrome (pss) produce functional igg against cholinoreceptor of exocrine glands modifying their activity. the aim of the present work was to demonstrate pss igg antibodies (pss igg) interacting with m 3 muscarinic acetylcholine receptors (machr) of rats submandibular glands that alter mucin release and production via phospholipase c (plc) and cycloox...

There is a newly emerging understanding that in the chaotic domain of isolated finite interacting many particle systems smoothed densities define the statistical description of these systems and these densities follow from embedded (two-body) random matrix ensembles and their various deformations. These ensembles predict that the smoothed form of matrix elements of a transition operator between...

A recent paper in Nature Communications shows that pseudokinase TRIB3 has a critical role in the development of diabetes-related cancers via interacting with SQSTM1, a selective autophagy receptor. Interrupting the TRIB3-SQSTM1 interaction using an α-helix peptide shows a significant antitumor effect both in normal and diabetic mice. This work provides a potential strategy against cancers in pa...

Innovations in Pharmaceutical Technology diversity – and in turn yielding stereochemically complex structures with diverse functional groups that are ideal for interacting specifically with biological target molecules. More importantly, nature has been ‘doing’combinational chemistry for aeons – not just a decade or two – and has been selecting products from this natural library that have specif...

background:the zinc-finger x linked (zfx) gene encodes a transcription factor that acts as a regulator of self-renewal of stem cells. due to the role of zfx in cell growth, understanding zfx protein-protein interactions helps to clarify its proper biological functions in signaling pathways. the aim of this study is to define zfx protein-protein interactions and the role of zfx in cell growth. m...

The main objectives of this article are 1) to introduces some basic postulates for quantum multi-particle systems, and 2) to develop a universal field theory for interacting multi-particle systems coupling both particle fields and interacting fields. By carefully examining the nature of interactions between multi-particles, we conclude that multi-particle systems must obey both the gauge symmet...

Fermi gases, collections of fermions such as neutrons and electrons, are found throughout nature, from solids to neutron stars. Interacting Fermi gases can form a superfluid or, for charged fermions, a superconductor. We have observed the superfluid phase transition in a strongly interacting Fermi gas by high-precision measurements of the local compressibility, density, and pressure. Our data c...