PURPOSE The aim of this study was to investigate the peripheral doses resulting from volumetric modulated arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) techniques in cervical cancer radiotherapy. METHODS Nine patients with cervical cancer had treatment planned with both VMAT and IMRT. A specially designed phantom was used for this study, with ion chambers placed at interest p...

Mobius FX, an add-on software module from Mobius Medical Systems™ for intensity-modulated radiation therapy (IMRT) quality assurance (QA), uses linac treatment logs to efficiently calculate and verify the 3D dose delivered to patients. An advantage of the Mobius FX module is that it does not require device positioning. In this study, we compared the Mobius FX with another QA option, ArcCheck, a...

Tumor tracking using a dynamic multileaf collimator (DMLC) represents a promising approach for intrafraction motion management in thoracic and abdominal cancer radiotherapy. In this work, we develop, empirically demonstrate, and characterize a novel 3D tracking algorithm for real-time, conformal, intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT)-based radiation...

Background: Recently we have upgraded our Varian Clinac 2100CD with a 6MV FFF beam, this upgrade being the first of its kind in our country. Even though the dosimetric characteristics of FFF beams have been reported both in experimental and Monte Carlo studies, application in planning and delivery is complex. The aim of this study was to validate the commissioning of upgraded FFF beams dosimetr...

PURPOSE Radiotherapy of the neck is known to cause carotid artery stenosis. We compared the carotid artery dose received between volumetric modulated arc therapy (VMAT) and conventional fixed-field intensity-modulated radiotherapy (IMRT) plans in patients with early glottic cancer. MATERIALS AND METHODS Twenty-one early glottic cancer patients who previously underwent definitive radiotherapy ...

BACKGROUND AND PURPOSE The purpose of this study was to assess plan quality and treatment time achievable with the new VMAT optimization tool implemented in the treatment planning system Oncentra MasterPlan® as compared to IMRT for Elekta SynergyS® linear accelerators. MATERIALS AND METHODS VMAT was implemented on a SynergyS® linear accelerator (Elekta Ltd., Crawley, UK) with Mosaiq® record a...

Radiation therapy has come a long way from treatment planning based on orthogonal radiographs with large margins around tumours. Advances in imaging and radiation planning software have led to three-dimensional conformal radiotherapy and, further, to intensity modulated radiotherapy (IMRT). IMRT permits sparing of normal tissues and hence dose-escalation to tumours. IMRT is the current standard...

Personalized radiation treatment is an important goal in oncology. As a result, one of the main challenges radiobiology today predicting patient?s tissue radiosensitivity so that personalized can be tailored to individual. For first time since 2016, group from Institute Oncology and Radiology Serbia has begun performing translational research field radiobiology. The aim these studies identify m...