Rural populations are undergoing rapid changes in both their livelihoods and land uses, with associated impacts on ecosystems, global biogeochemistry, and climate change. A primary challenge is, thus, to explain these shifts in terms of the actors and processes operating within a variety of land systems in order to understand how land users might respond locally to future changes in broader-sca...

Integrating the conservation of biodiversity by smallholder farmers with agricultural intensification is increasingly recognized as a leading priority of sustainability and food security amid global environmental and socioeconomic change. An international research project investigated the smallholder agrobiodiversity of maize (corn) in a global hotspot (Bolivia) undergoing significant intensifi...

Although the membrane process is recognized as a green technology and is considered as a key player in the process intensification movement, it is not widely known that the fabrication of membrane itself generates significant amount of waste. With the growing membrane market, more efforts must be placed on improving the sustainability of membrane fabrication such as replacing toxic organic solv...

1. Karch A, Krumkamp R, Kreuels B. Randomized, placebo-controlled trial or post hoc subgroup analysis: the importance of standardized and comprehensive reporting. J Infect Dis 2014; 210:158–9. 2. Hatano H, Strain MC, Scherzer R, et al. Increase in 2-LTR circles and decrease in D-dimer after raltegravir intensification in treated HIV-infected patients: a randomized, placebo-controlled trial. J I...

BACKGROUND A 2-year roadmap study was conducted to evaluate the efficacy and safety of tenofovir intensification at Week 24 in patients with chronic hepatitis B (CHB) receiving telbivudine. SCOPE A prospective multicenter study was conducted in treatment-naive patients with hepatitis B e antigen (HBeAg)-positive CHB. All patients received telbivudine (600 mg/day) until Week 24. Thereafter, pa...

This issue of Haematologica contains the results of a randomized clinical trial conducted by the Spanish Group PETHEMA (see Tables for acronyms), relative to the effects of late intensification therapy in adult acute lymphoblastic leukemia (ALL) [Ribera et al. Late intensification chemotherapy has not improved the results of intensive chemotherapy in adult acute lymphoblastic leukaemia. Results...