Exposure of Escherichia coli or mammalian cells to H2O2 results in cell death due to iron-mediated DNA damage. Since selenium compounds have been examined for their ability to act as antioxidants to neutralize radical species, and inorganic selenium compounds are used to supplement protein mixes, infant formula, and animal feed, determining the effect of these compounds on DNA damage under cond...

Selenium is an essential micronutrient in sheep, and deficiency can limit lamb growth and survival. To evaluate how different chemical forms of Se administered to mature ewes at comparative dosages affect ewe and progeny performance, 240 ewes were divided into 8 treatment groups (n = 30 each) and drenched weekly with no Se; at the maximum FDA-allowed concentration with inorganic Na-selenite or ...

Research interests in studying the biochemical nature of selenium have increased and the importance of this element as an essential micronutrient in many organisms has been well recognized. Selenium occurs in proteins in the form of the 21st amino acid, selenocysteine (SeCys or Sec). In this review, we describe the speciation analysis of the fish-specific selenoproteins and non-proteinous selen...

The 77Se NMR chemical shifts (δobsd(Se)) of p-YC6H4SeMe (1: Y ) H (a), OMe (b), Me (c), Cl (d), Br (e), COOR (f), and NO2 (g)) and p-YC6H4SePh (2) were determined or redetermined in chloroform-d. The δobsd(Se) values of 2, p-YC6H4SeR (R ) CN (3), Bz (4), H (5), Br (6), Et (7), C6H4Y-p (8), CHdCH2 (9), CHd CHCl-t (10), and CHCH2CCl2-cyclo (11)), 1,1′-[8-(p-YC6H4Se)C10H6Se]2 (12), and 1-(MeSe)-8-...

This study was conducted to determine the effects of vitamin E selenium ( Na2-SeO3) and organic selenium (Sel-Plex) on performance of broiler reared under chronic heat stress during summer season (30.043.5°C). A total of 180 one-day-old broiler chicks were randomly assigned to three selenium treatments, and two stocking density with two replicates of 15 birds each. The birds with a 3 x 2 factor...

Two types of mechanisms are considered in this discussion of the interactions between compounds of selenium and those of cadmium or mercury: one based on a direct chemical reaction between compounds of these elements and the other based on metabolic changes induced by selenium administration and modifying the dose-effect relationship indirectly, without a reaction between selenium and the metal...

The trace minerals zinc, copper, manganese, and selenium are components of a wide variety of enzymes and proteins that support metabolism, growth, production, and reproduction. Trace mineral supplements are added to dairy cattle rations to prevent mineral deficiencies, and supplementation has traditionally been provided in the form of inorganic salts. When these inorganic salts dissociate in th...

The biotransformation efficiency of alkylmercurial compounds was studied in rat liver, kidneys, blood, and brain after 2-week administration of methylmercuric chloride (MeHg) and ethylmercuric chloride (EtHg) at doses of 0.25 or 2.5 mg Hg/kg, alone or in combination with sodium selenite (Se) at a level of 0.5 mg Se/kg. Simultaneously, the level of metallothioneinlike proteins (MTP) and endogeno...