نتایج جستجو برای: innervation

تعداد نتایج: 9322  

Journal: :Journal of embryology and experimental morphology 1983
N G Laing A H Lamb

Chick embryo wing buds were transplanted to the pelvic region in place of, or in addition to, the hindlimb bud prior to innervation. The wrist muscle ulnimetacarpalis dorsalis (umd) was innervated by middle-dorsal or middle-ventral motoneurons in the lumbar lateral motor column (LMC) in a rostrocaudal position which varied with the rostrocaudal position of the wing. Despite the heterotopic inne...

Journal: :Annals of the rheumatic diseases 1995
P I Mapp

This review will describe the normal innervation of the joints, in particular the synovium, and then show how this changes in the rheumatoid arthritis (RA) joint in the human. Substance P will be described in detail, as an example of a particular neuropeptide. The concepts surrounding neuropeptide release and the role of neuropeptides in inflammatory joint disease (neurogenic inflammation) will...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Rayner Rodriguez-Diaz Stephan Speier Ruth Damaris Molano Alexander Formoso Itai Gans Midhat H Abdulreda Over Cabrera Judith Molina Alberto Fachado Camillo Ricordi Ingo Leibiger Antonello Pileggi Per-Olof Berggren Alejandro Caicedo

The autonomic nervous system is thought to modulate blood glucose homeostasis by regulating endocrine cell activity in the pancreatic islets of Langerhans. The role of islet innervation, however, has remained elusive because the direct effects of autonomic nervous input on islet cell physiology cannot be studied in the pancreas. Here, we used an in vivo model to study the role of islet nervous ...

Journal: :Journal of biological rhythms 2001
T J Bartness C K Song G E Demas

The suprachiasmatic nucleus (SCN) is the principal generator of circadian rhythms and is part of an entrainment system that synchronizes the animal with its environment. Here, we review the possible communication of timing information from the SCN to peripheral tissues involved in regulating fundamental physiological functions as revealed using a viral, transneuronal tract tracer, the pseudorab...

Journal: :Journal of neurophysiology 2009
Diana M Dimitrova Brian L Allman Mary S Shall Stephen J Goldberg

Single muscle fibers with multiple axonal endplates (multiply innervated fibers) are normally present in adult extraocular muscles (EOMs), while most other mammalian skeletal muscles contain fibers with a single myoneural junction. Recent findings by others led us to investigate for the presence of polyneuronal innervation (innervation of a single muscle fiber by >1 motoneuron) in the inferior ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
Natalia O Glebova David D Ginty

The neurotrophin nerve growth factor (NGF) plays a crucial role in the development of the sympathetic nervous system. In addition to being required for sympathetic neuron survival in vivo and in vitro, NGF has been shown to mediate axon growth in vitro. The role of NGF in sympathetic axon growth in vivo, however, is not clear because of its requirement for survival. This requirement can be circ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1981
J Mariani J P Changeux

The establishment of the adult innervation of Purkinje cells (PCs) by climbing fibers (CFs) was studied in the cerebellar vermis of the developing rat. Excitatory postsynaptic potentials (EPSPs) evoked in PCs by activation of the climbing fibers (CF-EPSPs) were recorded intracellularly from a total of 310 cells in young rats aged from 3 to 15 postnatal days. The CF system was activated by elect...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
A M LeMaster R F Krimm B M Davis T Noel M E Forbes J E Johnson K M Albers

Target-derived neurotrophin growth factors have significant effects on the development and maintenance of the mammalian somatosensory system. Studies of transgenic mice that overexpress neurotrophins NGF and neurotrophin 3 (NT-3) at high levels in skin have shown increased sensory neuron number and enhanced innervation of specific sensory ending types. The effects of two other members of this f...

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