In eukaryotic cell division, the kinetochore mediates chromosome attachment to spindle microtubules and acts as a scaffold for signaling pathways, ensuring the accuracy of chromosome segregation. The architecture of the kinetochore underlies its function in mitosis. In this issue, Hornung et al. (2014. J. Cell Biol. http://dx.doi.org/201403081) identify an unexpected linkage between the inner a...

This paper presents an all-analog iterative decoding network for an EPR4 magnetic recording system. A powerful serially concatenated architecture is considered, consisting of a simple outer code, an interleaver with reasonable size and a rate 1 EPR4 channel as inner code. The analog chip design is based on analog 0.18μm CMOS technology. Simulation results for both digital and analog implementat...

In this note, small amplitude free vibration of a double-beam system in presence of inner layer nonlinearity is investigated. The nonlinearity is due to inner layer material and is not related to large amplitude vibration. At first, frequencies of a double-beam system with linear inner layer are studied and categorized as synchronous and asynchronous frequencies. It is revealed that the inner l...

the term globalization undoubtedly has affected all parts of humanity life in current century. globalization as a comprehensive phenomenon has influenced economical, political, social and cultural aspects of our societies. contemporary architecture as a multidimensional category is depended on various factors and needs to be pursued in different fields, in order to reach to a perfect comprehend...

The Kedulan Temple, which was completely restored in 2019, showed many new things to be observed, moreover the discovery of three inscriptions on inner courtyard temple made it even more interesting study. This paper will discuss architectural and artistic aspects Temple its relation found with aim looking at characteristics architecture art their periodization Temple. research method used is d...

Acknowledgements First of all, I wish to thank my supervisors, Benoit Macq and Laurence Wolsey, for their guidance and continuous support during these four years. I am very grateful not only for their technical expertise but also for their ability to make me self-confident in moments of doubt. Moreover , working on a subject at the frontier of their respective research areas has been a very rew...

The kinetochore is often depicted as having a disk-like architecture in which the outer layer of proteins, which engage microtubules and control checkpoint signaling, are built on a static inner layer directly linked to CENP-A chromatin. Here, applying three-dimensional (3D) structural illumination microscopy (SIM) and stochastic optical reconstruction microscopy (STORM) to Xenopus egg extracts...