In 2003, US poison centers were contacted regarding ingestion of beta-blockers by 15,350 patients including 3766 (25%) under 6 years of age; 7415 (48%) were evaluated in healthcare facilities and 33 died. An evidence-based expert consensus process was used to create this guideline. Relevant articles were abstracted by a trained physician researcher. The first draft of the guideline was created ...

Coal mining and related industry can increase heavy metals (HMs) concentrations in soil, atmosphere and wheat, thereby posing metal-associated human health risk via food ingestion.  In this study, 58 samples of soil, wheat, and dust were collected from Xuzhou coal mine eastern China, six kinds of HMs Pb, Cd, Cu, Zn, As and Cr were studied for their spatial distribution in wheat, enrichment in d...

Introduction Anti-arrhythmic drug therapy carries an understood risk for toxic side effects, even at therapeutic doses. In cases of high dose ingestion these toxic effects can present rapidly with extra-cardiac symptoms, malignant arrhythmias and lifethreatening hemodynamic deterioration. Prescribing clinicians should maintain familiarity with the mechanisms and kinetics of the anti-arrhythmic ...

Objective(s): In veterinary medicine, zeolites are used as toxin binder in animal feed, ammonia purification of aquatic pools, animal smell and moisture control. This study investigated on the risk assessment of nano zeolite on development of embryonic chicken models, anomalies, tetratogenic and embryotoxic effects. Methods: Eggs (120 = n) were accidentally di...

ingested corrosive substances produce different injuries, ranging from minor gastro esophageal burns to death, depending on the agent type, amount, concentration, and duration of substance exposure. the purpose of this study was to investigate the outcomes and different causes of mortality in patients ingesting caustic substances. in a prospective study, between april 1999 and january 2006, a t...

results the electrophysiology laboratory staff received higher doses of ionizing radiation (17.2 ± 11.9 msv; p < 0.001). there was a significant positive correlation between the years of working experience and effective dose in the lens (p < 0.001). in general, our findings showed that the incidence of lens opacity was 79% (95% ci, 69.9-88.1) in participants with exposure (the case group) and o...

Hormesis, a dose-response phenomenon characterized by a low-dose stimulation and a high-dose inhibition, has been the object of controversy due to its challenging of basic understandings of the dose-response relationship and implications for risk assessment. The author addresses issues relating to the definition of hormesis, the relationship of hormesis to risk assessment and risk management, a...