conclusions use of ha in an algorithm model, is an extra and valuable tool for assessing liver necro inflammatory injuries- in parallel with liver biopsy- but more comprehensive studies are needed to approve the use of ha as an appropriate clinical tool. results there are several scientific studies indicating ha as a biomarker for high score fibrosis and cirrhosis in various liver diseases alon...

background and aims: cytomegalovirus (cmv) infection is very common in the population. virus belongs to the family herpesviridae, whose representatives are characterized by the ability to cause the human body's latent persistent infections. the goal of the study is to assess the cmvv infection frequency and pcr method in the choice of cmv in inflammatory eye disease, comparing with cmv pre...

Immune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading inflammation and irreversible organ damage. Laboratory diagnosis IMRDs includes wide range biomarkers (autoantibodies, acute phase proteins, cytokines, markers endothelial damage, components the complement system, immunoglobulins, cryoglo...

BACKGROUND Type 1 diabetes mellitus is a chronic inflammatory disease involving insulin producing β-cells destroyed by the conjoined action of auto reactive T-cells, inflammatory cytokines and monocytic cells. The aim of this study was to elucidate the status of pro-inflammatory cytokines and biochemical markers and possible correlation of these factors towards outcome of the disease. METHODS...

Abstract Background Identification of molecular markers, such as miRNAs is promising for the diagnosis asthma and its clinical phenotypes. The aim this study was to examine changes in expression selected microRNAs plasma exosomal fractions severe patients. determined relation inflammatory markers. Method Severe patients (n = 30) healthy subjects were among individuals referred allergy clinic. B...

The aim of this study was to evaluate the individual diagnostic utility of tumour and inflammatory markers in patients with different pulmonary diseases. The usefulness of neuron-specific enolase (NSE), carcino-embryonic antigen (CEA), serum pro-gastrin releasing peptide (ProGRP) and CYFRA 21-1, as tumour markers, and C-reactive protein (CRP) and tumour necrosis factor-alpha (TNFalpha) as infla...

This study aimed to evaluate the concentrations of C-reactive protein (CRP), Procalcitonin (PCT), and ceruloplasmin (Cp), which are potential biochemical markers inflammatory process in dogs naturally infected with Ehrlichiosis. A total 20 dogs, 8 clinically healthy (Healthy group) 12 mono-infected Ehrlichia spp. (Ehrlichia were included study. Dogs group selected from those showing clinical si...

Although some studies revealed a positive relationship between vitamin D3 deficiency and inflammatory markers, there have been also many studies that failed to find this relationship. The aim of this large scaled study is to determine the association between the level of plasma 25 hydroxy vitamin D3 [25-(OH) D3] and inflammatory markers in the general population without chronic kidney disease (...

Lipopolysaccharide (LPS) is responsible for causing inflammation leading to septic shock or organ failure. During treatment of infection, high amount of LPS is released in blood circulation due to immediate lysis of bacteria. Since liver helps in clearing LPS from the body, hence it remains the primary target to be stimulated by LPS releasing vigorous amount of inflammatory molecules leading to...