Holoprosencephaly is associated with a diagnostic face approximately 80% of the time. We report three siblings with alobar holoprosencephaly and essentially normal faces. A similar family was reported by Khan et al. [1970: Dev Med Child Neurol 12:71-76]. Alobar holoprosencephaly with essentially normal faces has also been observed in infants of diabetic mothers [Barr et al., 1983: J Pediatr 102...

Background: Despite significantly increased input from multidisciplinary teams during antenatal period, pregnancy outcome from women with type 1, type 2 and gestational diabetes mellitus (DM) remain substantially worse than that of general obstetric population. In Iraq, the true magnitude of infant of diabetic mother (IDM) is not well known as health system has been badly eroded over the period...

Converging evidence from multiple lines of research has implicated medial temporal lobe (MTL) structures, including the hippocampus, in the conscious recollection of facts and events (i.e., declarative memory; Squire, 1992; see Chapter 1). Some of the most compelling support for this association comes from studies in adults showing that discrete lesions to the hippocampus and surrounding MTL re...

Twelve newborn infants of poorly-controlled diabetic mothers were transferred from outlying maternity hospitals for neonatal intensive care. Respiratory distress and cardiomegaly were the presenting signs. Ten infants were large for dates (macrosomic) and had echocardiographic evidence of myocardial hypertrophy, reduced ejection time, and systolic anterior movement of the mitral valve (in 6 inf...

Diabetic mothers affect their offspring during pregnancy, sometimes giving rise to the complete symptoms of diabetic fetopathia with the typical appearance of the child high birth weight, hyperinsulinism, etc. Some of these traits have also been reported to appear in the infants some time before the onset of diabetes in the mother, but no prospective study of infants born to truly prediabetic m...

Healthy term babies undergo a physiological nadir in serum calcium levels by 24-48 hours of age. The nadir may be related to the delayed response of parathyroid and calcitonin hormones in a newborn. This nadir may drop to hypocalcemic levels in high-risk neonates including infants of diabetic mothers, preterm infants and infants with perinatal asphyxia. The early onset hypocalcemia which presen...

INTRODUCTION Since research investigating IGF-1 levels in breast milk are few, the goal of this study was to analyze the IGF-1 levels in the breast milk of diabetic mothers as well as in the serum of their newborn babies and to identify what relationship exists between blood serum and IGF-1 milk levels through patient measurement of mothers and their babies. METHODS This case control study wa...

Background Bacterial colonization during and shortly after birth are common in newborn infants. The aim of this study was to determine the umbilical cord bacterial colonization in newborn infants rooming in with mothers and neonates admitted to neonatal intensive care unit (NICU). Materials and Methods In a cross-sectional study, 180 newborn infants were studied in three groups including: newbo...

background and aim:  the stress resulting from premature delivery and the related neonatal care induces psychological and physical pressure on the mothers, and adversely affects their feeling of comfort. it seems that spiritual care as a sort of communication with a higher power (god) can bring peace to the stressed mothers, and prevent anxiety. therefore, this study was designed to evaluate th...