Introduction: Venetoclax-based therapy is standard for pts with relapsed/refractory (R/R) CLL previously treated a covalent BTK inhibitor (cBTKi). Pirtobrutinib highly selective, non-covalent (reversible) BTKi designed to overcome pharmacologic limitations of cBTKi and restore inhibition has demonstrated marked efficacy favorable safety profile. This unanchored MAIC estimates the treatment effe...

image denoising by block matching and threedimensionaltransform filtering (bm3d) is a two steps state-ofthe-art algorithm that uses the redundancy of similar blocks innoisy image for removing noise. similar blocks which can havesome overlap are found by a block matching method and groupedto make 3-d blocks for 3-d transform filtering. in this paper wepropose a new block grouping algorithm in th...

In the light of this interest, I designed "Rabbi", a conversational storytelling system that simulates a rabbi with a repertoire of Hasidic stories to offer as indirect counsel. It approaches narrative through a psycho-social theory of discourse which looks not only at the linguistic structures of the text but also at the socio-cultural context in which the contract between teller and listener ...

This paper estimates the effect of involuntary job loss on smoking behavior and body weight using German Socio-Economic Panel Study data. Baseline nonsmokers are more likely to start smoking due to job loss, while smokers do not intensify smoking. Job loss increases body weight slightly, but significantly. In particular, single individuals as well as those with lower health or socioeconomic sta...

We consider a model in which an outcome depends on two discrete treatment variables, where one treatment is given before the other. We formulate a three-equation triangular system with weak separability conditions. Without assuming assignment is random, we establish the identification of an average structural function using two-step matching. We also consider decomposing the effect of the first...

We propose a scheme for infrared single-photon detection based on two-photon absorption at room temperature in Si avalanche photodiodes, where the detected photon’s energy is lower than the band gap and the energy difference is complemented by a pump field. A quantum nonperturbative model is developed for nondegenerate two-photon absorption in direct and indirect semiconductors yielding proper ...