In this issue of Blood, Kabiri and coworkers report the hematopoietic deletion of the endoplasmic reticulum–localized O-acyltransferase porcupine (PORCN), which is necessary for acylation of Wnts in the endoplasmic reticulum, enabling their secretion and binding to the frizzled receptors. Unexpectedly, the absence of secreted Wnt factors does not have major effects on steady-state in vivo hemat...

A new species, Cryptosporidium ubiquitum, previously identified as the Cryptosporidium cervine genotype and infrequently as the cervid, W4 or genotype 3 genotype, is described. In published studies this genotype was reported in wild and domesticated ruminants, rodents, carnivores and primates including humans. In the present study oocysts were found in feces from a captive prehensile-tailed por...

AIM To identify the types of endocrine cells in the pancreas of the Sunda porcupine (Hystrix javanica) and its immunolocalization. MATERIALS AND METHODS Five adult H. javanica were used without sexual distinction. The presences of endocrine cells (glucagon, insulin, somatostatin, and pancreatic polypeptide [PP]) in pancreatic tissues were detected using the avidin-biotin-peroxidase complex me...

Interactions between the internal regulation and environment drive biophysiological patterns of amphibians. It is well known phenomenon that newts in northern hemisphere are tend to have hibernation strategies winter seasons. However, activity record for quite rare. Therefore, we would like report two cases from Anatolia, Turkey via newt species: The banded (Ommatotriton ophryticus) Ordu Balkan...

weirs have widely been used for the flow measurement, flow diversion and its control in the open channels. attempts have been made to study flow over different shapes of normal weirs, side weirs and oblique weirs. this paper is connected with the development of the discharge coefficient measurement. in the present study four different weirs in different height are considered for validation purp...

The amount of wave overtopping at coastal structures such as vertical caisson breakwaters is strongly dependent on the angle attack. reducing effects oblique waves compared to perpendicular attack has been studied by means three-dimensional basin tests. In these physical model tests breakwater exposed conditions with angles between and very (i.e. 0°–75° in steps 15°). Short-crested long-crested...

the employment is a requisite if one wants to have a normal life, decent meals and a place to stay; it socializes the people and gives them some survival and esteem feeling in the society. besides that employment boosts personal well fear, morale integrity and self confidence. in india economy is diverse where employees are employed in agriculture, handicraft, a wide range of modern industries,...