Treatment of in-stent restenosis lesions, especially calcified with stent underexpansion, generally requires more complex techniques, such as rotational atherectomy. The case reported is a male patient 99% focal lesion at the origin first diagonal branch, where two stents were implanted 14 years ago. After failure balloon angioplasty alone, ablation plaque and part struts was performed using at...

Intravascular ultrasound examination (ICSI) allows to assess the nature of atherosclerotic plaque, degree significance and extent stenosis, as well monitor position stent in lumen coronary artery. Insufficient opening stent, unrecognized during angiographic control, can lead thrombosis or restenosis early long term. The clinical case presented publication demonstrates difference between results...

Despite the considerable progress made in the stent development in the last decades, cardiovascular diseases remain the main cause of death in western countries. Beside the benefits offered by the development of different drug-eluting stents, the coronary revascularization bears also the life-threatening risks of in-stent thrombosis and restenosis. Research on new therapeutic strategies is impa...

BACKGROUND Experimental studies suggest that arterial injury and inflammation lead to increased neointimal growth after stenting. Despite the increased use of coronary stents in humans, there are only limited pathological data on the morphological features of in-stent restenosis. METHODS AND RESULTS Detailed histology was performed on 116 stents, implanted > or =90 days in 87 coronary arterie...

BACKGROUND AND PURPOSE Restenosis after carotid angioplasty (with or without stent) is associated with increased rate of stroke and death. Our aim was to determine risk and predictive factors related to carotid restenosis post carotid angioplasty and its association to recurrent cerebrovascular events. METHODS All consecutive patients with carotid stenosis treated with angioplasty (n=1060) in...

background: recently, different investigators have studied the possibility of radiation therapy in restenosis prevention and have shown promising results. in this study a unique radioactive source for intra vascular brachytherapy (ivbt) was investigated. the two-dimensional dose distribution in water for a 32p ivbt stent has been calculated. the pure beta emitter source 32p has been coated on p...

OBJECTIVES This study evaluated the clinical safety and long-term results of rotational atherectomy (RA) followed by low-pressure balloon dilatation (percutaneous transluminal coronary angioplasty [PTCA]) for the treatment of in-stent restenosis (ISR). BACKGROUND In-stent restenosis is associated with a high incidence of recurrence after interventional treatment. Because ISR is due to neointi...

UNLABELLED Coronary stent implantation is an increasingly accepted revascularization method. The 20%-30% restenosis rate during the first 6 mo requires a close follow-up of the patients. Since there is very little data available defining the role of perfusion scintigraphy in the management of this population, the aim of this study was to assess the diagnostic performance of stress myocardial pe...

BACKGROUND The first clinical study of paclitaxel-eluting stent for de novo lesions showed promising results. We performed the TAXUS III trial to evaluate the feasibility and safety of paclitaxel-eluting stent for the treatment of in-stent restenosis (ISR). METHODS AND RESULTS The TAXUS III trial was a single-arm, 2-center study that enrolled 28 patients with ISR meeting the criteria of lesio...

BACKGROUND The factors associated with the occurrence of restenosis after sirolimus-eluting stent (SES) implantation in complex cases are currently unknown. METHODS AND RESULTS A cohort of consecutive complex patients treated with SES implantation was selected according to the following criteria: (1) treatment of acute myocardial infarction, (2) treatment of in-stent restenosis, (3) 2.25-mm d...