نتایج جستجو برای: immunotoxicity

تعداد نتایج: 652  

Journal: :Journal of toxicology and environmental health. Part A 2008
Chiharu Mori Brenda Morsey Milton Levin Timothy S Gorton Sylvain De Guise

Organochlorines (OC) are lipophilic and stable, and therefore accumulate in tissues of top predators, such as marine mammals. While the immunomodulatory effects of individual OC have been studied in lab animals, their effects in other species (such as marine mammals) and the possible interactions between chemicals in mixtures are not well understood. This study investigated the immunomodulatory...

2016
Fanghui Li Hui Wang Jinfeng Liu Jiebo Lin Aibing Zeng Weiming Ai Xuedong Wang Randy A. Dahlgren Huili Wang

Fluoroquinolones and tetracyclines are known as β-diketone antibiotics (DKAs) because of bearing a diketone group in their molecular structure. DKAs are the most widely used antibiotics to prevent generation of disease in humans and animals and to suppress bacterial growth in aquaculture. In recent years, overuse of DKAs has caused serious environmental risk due to their pseudo-persistence in t...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2006
Stéphane Pillet Michele D'Elia Jacques Bernier Jean-Marie Bouquegneau Michel Fournier Daniel G Cyr

A wide range of toxic effects has been associated with cadmium (Cd) exposure in mammals. However, the physiological factors that modulate these effects have received limited attention. We have previously demonstrated that neonatal exposure of rats to Cd during lactation results in sex-specific immunotoxic effects in both juvenile and adult rats. The objectives of this study were to determine th...

2013
Mahmoud Elsabahy Shiyi Zhang Fuwu Zhang Zhou J. Deng Young H. Lim Hai Wang Perouza Parsamian Paula T. Hammond Karen L. Wooley

The construction of nanostructures from biodegradable precursors and shell/core crosslinking have been pursued as strategies to solve the problems of toxicity and limited stability, respectively. Polyphosphoester (PPE)-based micelles and crosslinked nanoparticles with non-ionic, anionic, cationic, and zwitterionic surface characteristics for potential packaging and delivery of therapeutic and d...

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