A fibroadenoma was diagnosed in the mammary gland of a lamb by immunohistochemical method andmeasurement of oestradiol hormone. The tumor was characterized by an encapsulated firm mass with acreamy-white cut surface. Histologically, it consisted of variably-sized sinus ducts, covered by a single ormultiple layers of proliferated epithelial cells, and embedded in a loose connective tissue. Immun...

Pathological examination has been the gold standard for diagnosis in cancer and its role has also included the elucidation of etiology, pathogenesis, clinicopathological correlation, and prognostication. The advent of newer technologies and the realization that breast cancer is heterogeneous has shifted the focus to prognostication, with increased attention being paid to the identification of m...

Background: Basal-like breast cancer has been extensively characterized on the basis of gene expression profiles, but it is becoming increasingly common for these tumors to be defined on the basis of immunohistochemical (IHC) staining patterns, particularly in retrospective studies where material for expression profiling may not be available. The IHC pattern that best defines basal-like tumors ...

The Phomopsis is a genus of imperfect plant pathogenic fungus whose hosts comprise several species in different regions of the world, such as grapes, soybean, acacia, hollyhock, velvetleaf, and several other plants. In this study, samples collected from hollyhock, velvetleaf, purple bauhinia, and acacia plants suspected to be infected with Phomopsis fungi. Samples were culture...

The phenotypic differentiation of systemic macrophages that have infiltrated the central nervous system, pericytes, perivascular macrophages, and the "real" resident microglial cells is a major immunocytochemical and immunohistochemical concern for all users of cultures of brain cells and brain sections. It is not only important in assessing the purity of cell cultures; it is also of fundamenta...

Thioredoxin-Interacting Protein (TXNIP) has been shown to have significant pathogenic roles in many human diseases, particularly those associated with diabetes and hyperglycemia. Its main mode of action is sequester thioredoxins, resulting enhanced oxidative stress. The aim this study was identify if cellular expression TXNIP aged Alzheimer’s disease (AD) brains correlated pathological structur...

Introduction: Liver is the most commonly involved organ by metastatic disease. Secondary tumors are more frequent lesion forming than 75%, while primary cancers of liver formed less 25%. Imaging according to LI-RAD can give a clue for nature live particularly hepatocellular carcinoma. biopsy still golden standard surveillance histopathological diagnosis tumor; however, it traumatic procedure, b...

BACKGROUND: Resident macrophages of the myocardium are necessary for normal development and functioning cardiovascular system play an important role in pathogenesis a number diseases.
 AIM: To develop universal methodological approach immunohistochemical identification human rat myocardium.
 MATERIAL AND METHODS: For study, samples people both sexes aged from 28 to 52 years (n=7) Wist...

Triple negative breast cancer (TNBC) [negative for expression of estrogen and progesterone receptors (ER, PR) and HER2÷neu protein] represent a subtype of breast cancer associated with poor prognosis and highly aggressive behavior. The characterization of stem cell in this type of carcinoma could determine the appearance of new ideas concerning origin and evolution. There is an impressive amoun...