Twelve new imidazole-based potential bi- and tridentate ligands were synthesized and characterized. Whereas in the first series the alpha-amino acid and imidazole moieties were linked by an amino bond, in the second series the tridentate ligands, containing two imidazole groups, were separated by an amide bond. The first series was obtained by the reductive amination of 2-phenylimidazole-4-carb...

In the current work, azo ligand and its Pd (Ⅱ), Cd Zn (Ⅱ) Hg complexes were synthesized, characterized their spectroscopic characteristics studied. The new was synthesized from coupling reaction between 4,5-bis(4-methoxy phenyl)imidazole diazonium salt of 4-Amino benzoic acid in an alkaline medium at 0-5 ᵒC. metal prepared by metals chlorides. All compounds FT-IR, 1H-NMR, Mass spectral analysis...

A general two-level latent variable model is developed to provide a comprehensive framework for model comparison of various submodels. Nonlinear relationships among the latent variables in the structural equations at both levels, as well as the effects of fixed covariates in the measurement and structural equations at both levels, can be analyzed within the framework. Moreover, the methodology ...

Several imidazole derivatives bearing titratable charged groups adjacent to the imidazole ring have been studied by nuclear magnetic resonance. Curves relating the chemical shift values of the C-2 and C-4 ring proton resonance signals of these compounds to the solvent pH have been examined. These curves clearly demonstrate effects corresponding to the titration of the neighboring charged groups...

In the title compound, [Pd(C(9)H(12)N)Cl(C(4)H(6)N(2))], which was synthesized from the reaction of 1-methyl-imidazole with dimeric dichloridobis[2-(dimethyl-amino)-benz-yl]palla-dium(II), the ring-deprotonated N,N-dimethyl-benzyl-amine ligand acts in a C,N-bidentate fashion. The dihedral angle between the ring of the 1-methyl-imidazole ligand and the palladacycle plane is 57.88 (16)°. The two ...

Three distal imidazole pickets in a cytochrome c oxidase (CcO) model form a pocket hosting a cluster of water molecules. The cluster makes the ferrous heme low spin, and consequently the O(2) binding slow. The nature of the rigid proximal imidazole tail favors a high spin/low spin cross-over. The O(2) binding rate is enhanced either by removing the water, increasing the hydrophobicity of the ga...

Small unilamellar vesicles (approximately 100 nm in diameter) form spontaneously in aqueous mixtures of histidine and sodium dodecyl benzenesulfonate. By manipulating pH, a gradual transition from micelles to vesicles to bilayers to precipitate is observed. The self-assembly of vesicles occurs over a wide range of compositions when the solution pH is lower than 6.0, the pKa of the imidazole moi...

Cyclic voltammogram and differential pulse polarograph of octaethyl porphyrin iron(III) chloride in dichloromethane was investigated in the presence of pyridine, imidazole and collidine. Values of E1/2 for FeIII/FeII redox reaction were monitored as a function of axial group concentration, and on the basis of these data, an overall oxidation-reduction and ligand addition scheme was formulated. ...

The incorporation of potentially catalytic groups in DNA is of interest for the in vitro selection of novel deoxyribozymes. A series of 10 C5-modified analogues of 2'-deoxyuridine triphosphate have been synthesised that possess side chains of differing flexibility and bearing a primary amino or imidazole functionality. For each series of nucleotide analogues differing degrees of flexibility of ...