The effects of SK-896, a new human motilin analogue ([Leu13]motilin-Hse), on digestive tract motility in postoperative ileus were evaluated in a dog model of ileus after laparotomy. SK-896 was intravenously administered at 0.17, 0.33 and 0.67 microg/kg starting soon after operation and then at 6-h intervals, for a total of 9 times. SK-896 progressively, dose-dependently and significantly increa...

AIMS/INTRODUCTION Gallstone sigmoid ileus is a rare condition that presents with symptoms of large bowel obstruction secondary to a gallstone impacted within the sigmoid colon. This arises because of three primary factors: cholelithiasis causing a cholecystoenteric fistula; a gallstone large enough to obstruct the bowel lumen; and narrowing of the bowel. We describe 3 patients treated in a dist...

An 85-year-old woman was an outpatient treated at Tokyo Rosai Hospital for cirrhosis caused by hepatitis B. She had previously been diagnosed as having common bile duct stones, for which she underwent endoscopic retrograde cholangiopancreatography (ERCP). However, as stone removal was unsuccessful, a plastic stent was placed after endoscopic sphincterotomy. In October 2012, the stent was replac...

PURPOSE One of the major causes of bowel obstruction in extremely premature infants is a meconium obstruction. However, there are many challenges not only in the recognition and diagnosis, but also in the management of meconium obstruction. This study aimed to find perioperative clinical features and determine the postoperative course of meconium-related ileus in very low birth weight (VLBW) an...

BACKGROUND AND AIM Nonoperative management of cases of adhesive intestinal obstruction would be ideal, especially for patients who have recently undergone surgery to relieve the same condition. We aimed to examine whether hyperbaric oxygen (HBO) therapy might have therapeutic potential for the treatment of postoperative paralytic ileus and recurrent adhesive intestinal obstruction soon after su...

Gall-stone ileus associated with tuberculous strictures is an uncommon cause of bowel obstruction related to a cholecystoenteric fistula. The stone usually obstructs the narrowest part of the intestine. The patient whose intestine is strictured due to tuberculosis or other disease, the stone can impact that part of the strictured area. We report such a case of gall-stone ileus in a patient of 8...

Constipation is a side effect of antipsychotic drugs that have high affinity for muscarinic cholinergic receptors. In addition, ileus is an important side effect of antipsychotic treatment, with potentially morbid and mortal consequences if early detection fails. In this report, a colonic ileus case is described in a patient with schizophrenia under the treatment of paliperidone palmitate. Cons...

The symptoms of Crohn's disease can vary significantly among afflicted individuals. It is a chronic inflammatory disease, which has many complications involving gastrointestinal and other symptoms. The diagnosis of gallstone ileus is difficult in Crohn's disease and an early diagnosis can reduce mortality. We present a case of 72 year old female with known Crohn's disease with acute right iliac...

Sigmoid and caecal volvulus: Describes rotation of the gut on its mesenteric axis. The sigmoid colon is the most common site of volvulus and accounts for 5% of large bowel obstruction. It is usually seen in the elderly or those with psychiatric illness. It is the most common cause of intestinal obstruction in Africa and Asia, where the incidence is 10 times higher than in Europe or North Americ...

A 68-year-old gentleman presented with abdominal distension and faeculent vomiting. He had a background of cerebral palsy with learning difficulties making history taking problematic. A CT scan suggested small bowel obstruction secondary to gallstone ileus. The most likely differential diagnosis was an inguinal hernia which was noted adjacent to the transition point. Laparotomy revealed grossly...