background and objectives: timely diagnosis of leptospirosis is essential for an effective treatment. large diversity of clinical symptoms has led leptospirosis diagnosis difficult. researchers have conducted many tests with wide-range of sensitivity and specificity to achieve novel diagnostic procedures which have higher sensitivity and specificity compared with previous tests and which are mo...

conclusions based on the findings, application of recombinant arcaga antigen for the detection of h. pylori infection is a simple, rapid, and brief non-invasive method. therefore, it can be suggested as an appropriate antigen for h. pylori detection kits. results we investigated caga protein, using the immunoblotting method in stool samples, which were already identified as positive by the appl...

background alcoholic hepatitis (ah) is an acute manifestation of alcoholic liver disease with high mortality rates. objectives our aim was to study the molecular mechanisms of ah. materials and methods the differentially expressed genes (degs) in liver between ah and control cases were identified by analyzing the gse28619 microarray data using t-test. the kyoto encyclopedia of genes and genomes...

an experiment was conducted to study wheat grain protein increasing through foliar application of nitrogen afterflowering. the rcbd design was analysed with three replications and four n-treatments as foliar application as(n0=0, n1=4kg.ha-1 urea, n2=8kg.ha-1 urea, n3=4kg.ha-1 ammonium sulfate). results showed that seed proteincontent increased significantly by foliar application of nitrogen. da...

Polymorphic light eruption (PLE) is a chronic intermittent skin disease that develops episodes after sun exposure, most often in spring or early summer. Although the pathogenesis not fully understood, evidence indicates microbiome may play crucial role. Preclinical data have shown can regulate UV-induced cytokine expression and modulate subsequent immune response. We therefore hypothesized of P...

Abstract Kawasaki Disease (KD), a pediatric acute febrile illness and systemic vasculitis, is the leading cause of acquired heart diseases in children. Coronary artery aneurysms (CAAs) occur up to 25% untreated children, which reduced 5% with intravenous immunoglobulin (IVIG) treatment. However, 20% KD patients are refractory IVIG at higher risk CAAs, highlighting need characterize mechanisms m...

PURPOSE To evaluate the effect of anti-interleukin-33 (anti-IL-33) on a mouse model of ovalbumin (OVA)-induced acute kidney injury (AKI). METHODS Twenty-four female BALB/c mice were assigned to 4 groups: group A (control, n=6) was administered sterile saline intraperitoneally (i.p.) and intranasally (i.n.); group B (allergic, n=6) was administered i.p./i.n. OVA challenge; group C (null treatm...

objectives the overall goal of this study was to carry out a set of comparative analyses of arsr gene in plasmid r773 and bacterial chromosome from escherichia coli bl-21(de3). methods pdb and ncbi databases and chimera, mega4, clc main workbench software and 3d-jigsaw and embl-ebi servers were applied to perform this study. by using these software and servers, multiple analyses including deter...

Immune checkpoint inhibitors (ICIs) are oncologic therapies that induce non-specific immune activation, which may lead to cutaneous immune-related adverse events (cirAEs) mimic various inflammatory skin diseases. The pathogenesis of these cirAEs is unknown. We report the profile ICI-induced lichen planus (LP) and vitiligo in a prostate cancer patient on cemiplimab. Baseline post-skin-directed t...