نتایج جستجو برای: il1b

تعداد نتایج: 724  

2013
Yoshie Yoshikawa Yusuke Sasahara Katsuyuki Takeuchi Yoshimasa Tsujimoto Takashi Hashida-Okado Yukio Kitano Tomoko Hashimoto-Tamaoki

We cultured human hair follicle-derived keratinocytes (FDKs) from plucked hairs. To gain insight into gene expression signatures that can distinguish atopic dermatitis from non-atopic controls without skin biopsies, we undertook a comparative study of gene expression in FDKs from adult donors with atopic dermatitis and non-atopic donors. FDK primary cultures (atopic dermatitis, n = 11; non-atop...

2011
Christina Persson Paulo Canedo José C. Machado Emad M. El-Omar David Forman

To evaluate the association between gastric cancer susceptibility and inflammation-related gene polymorphisms, the authors conducted a series of meta-analyses using a predefined protocol. Genes investigated were those coding for the interleukin (IL) proteins (IL1B, IL1RN, IL8, and IL10) and for tumor necrosis factor-alpha. Gastric cancers were stratified by histologic subtype and anatomic subsi...

Journal: :Collegium antropologicum 2013
Zoran Loncar Goran Curić Ana Havelka Mestrović Vlatko Mićković Morana Bilić

The aim of this study was to analyze the association between single nucleotide polymorphism (SNP) in IL1B (rs1143 634) and IL1RN (rs2234677) with chronic low back pain (LBP) in chronic post-traumatic stress disorder (PTSD). A total of 406 war veterans from 1991-1995 war in Croatia participated in this study. They were divided into four groups, according to psychiatric interview, psychometric te...

Journal: :Revista medica de Chile 2009
Néstor J López Antonio Quintero Marcelo Llancaqueo Lilian Jara

BACKGROUND Studies investigating effects of periodontal treatment (PT) on markers of inflammation in healthy subjects show conflicting results. Few studies have investigated the effects of PT among subjects with coronary heart disease (CHD) risk factors. AIM To report the results of a pilot prospective study on the effects of periodontal treatment on markers of inflammation among subjects wit...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Lukas A Hefler Christoph Grimm Tilmann Lantzsch Dieter Lampe Sepp Leodolter Heinz Koelbl Georg Heinze Alexander Reinthaller Dan Tong-Cacsire Clemens Tempfer Robert Zeillinger

PURPOSE Genetic polymorphisms of cytokine-encoding genes are known to predispose to malignant disease. Interleukin (IL)-1 and IL-6 are crucially involved in breast carcinogenesis. Whether polymorphisms of the genes encoding IL-1 (IL1) and IL-6 (IL6) also influence breast cancer risk is unknown. EXPERIMENTAL DESIGN In the present case-control study, we ascertained three polymorphisms of the IL...

2015
Ei Leen Liew Marito Araki Yumi Hironaka Seiichi Mori Tuan Zea Tan Soji Morishita Yoko Edahiro Akimichi Ohsaka Norio Komatsu

BACKGROUND The gain-of-function mutation JAK2V617F is frequently found in Philadelphia-chromosome-negative myeloproliferative neoplasm (MPN) patients. However, the tumorigenic properties of JAK2V617F have mostly been characterized in in vivo and in vitro murine models due to the lack of appropriate human cell lines. METHODS Using the multipotent hematologic cell line UT-7/GM, we established D...

Journal: :American journal of epidemiology 2011
Christina Persson Paulo Canedo José C Machado Emad M El-Omar David Forman

To evaluate the association between gastric cancer susceptibility and inflammation-related gene polymorphisms, the authors conducted a series of meta-analyses using a predefined protocol. Genes investigated were those coding for the interleukin (IL) proteins (IL1B, IL1RN, IL8, and IL10) and for tumor necrosis factor-alpha. Gastric cancers were stratified by histologic subtype and anatomic subsi...

2015
Anna C. Pfalzer Paula-Dene C. Nesbeth Laurence D. Parnell Lakshmanan K. Iyer Zhenhua Liu Anne V. Kane C-Y. Oliver Chen Albert K. Tai Thomas A. Bowman Martin S. Obin Joel B. Mason Andrew S. Greenberg Sang-Woon Choi Jacob Selhub Ligi Paul Jimmy W. Crott Markus M. Heimesaat

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on the intestinal microbiome and metabolome in a mouse model of CRC. Apc1638N mice were made obese by ...

Journal: :Fish & shellfish immunology 2015
Seyed Hossein Hoseinifar Mohsen Khalili Rudabeh Rufchaei Mojtaba Raeisi Marzieh Attar Héctor Cordero M Ángeles Esteban

The aim of this study was to investigate the effects of date palm fruit extracts (DPFE) on skin mucosal immunity, immune related genes expression and growth performance of fry common carp (Cyprinus carpio). One hundred and twenty specimens (4.06 ± 0.13 g) were supplied and allocated into six aquaria; specimens in three aquaria were fed non-supplemented diet (control) while the fish in the other...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2008
J B A Crusius F Canzian G Capellá A S Peña G Pera N Sala A Agudo F Rico G Del Giudice D Palli M Plebani H Boeing H B Bueno-de-Mesquita F Carneiro V Pala V E Save P Vineis R Tumino S Panico G Berglund J Manjer R Stenling G Hallmans C Martínez M Dorronsoro A Barricarte C Navarro J R Quirós N Allen T J Key S Binghan C Caldas J Linseisen R Kaaks K Overvad A Tjønneland F C Büchner P H M Peeters M E Numans F Clavel-Chapelon A Trichopoulou E Lund M Jenab S Rinaldi P Ferrari E Riboli C A González

BACKGROUND The relative contribution to gastric cancer (GC) risk of variants in genes that determine the inflammatory response remains mostly unknown and results from genotyping studies are inconsistent. PATIENTS AND METHODS A nested case-control study within the prospective European Prospective Investigation into Cancer and Nutrition cohort was carried out, including 248 gastric adenocarcino...

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