Whether there is an association between coeliac disease and epilepsy is uncertain. Recently, a syndrome of coeliac disease, occipital lobe epilepsy and cerebral calcification has been described, mostly in Italy. We measured the prevalence of coeliac disease in patients attending a seizure clinic, and investigated whether cerebral calcification occurred in patients with both coeliac disease and ...

Background/aim: In this study, we aimed to investigate different types of celiac antibodies in psoriasis patients and see if the presence was associated with other variables. Materials methods: We included plaque who were followed up our dermatology clinic between February 2019 2021 added a healthy control group for comparison. The studied serum antitissue transglutaminase (tTG)-IgA, tTG-IgG, a...

Diseases associated with immunoglobulin A (IgA) antibody include linear IgA dermatosis, IgA nephropathy, Celiac disease, Henoch-Schönlein purpura, etc. Although usually idiopathic, IgA antibody is occasionally induced by drugs (e.g., vancomycin, carbamazepine, ceftriaxone, and cyclosporine), malignancies, infections, and other causes. So far, only a few cases of IgA bullous dermatosis coexistin...

Abstract Despite ongoing efforts to characterize the host response toward SARS-CoV-2, a major gap in our knowledge still exists regarding magnitude and duration of humoral response. Analysis antibody mild versus moderate/severe patients, using new developed quantitative electrochemiluminescent assay for detecting IgM/IgA/IgG antibodies SARS-CoV-2 antigens, revealed rapid onset IgG/IgA antibodie...

Three defense functions of immunoglobulin A (IgA), immune exclusion, intracellular neutralization, and virus excretion, were assessed in a measles virus model using polarized epithelial cells expressing the polymeric immunoglobulin receptor and monoclonal antibodies against the viral H and F envelope proteins and the internal N protein. Anti-H IgA was the most effective antibody at preventing i...

Sequential serum samples of 13 patients with acute farmer's lung (FL) taken during a follow-up of 18-36 months, were tested for antibodies of immunoglobulin G (IgG), IgA, IgM and IgE classes against Thermoactinomyces vulgaris and Micropolyspora faeni, and compared with contemporary lung function parameters. In the acute phase, antibodies of several Ig classes were present, those of IgG and IgA ...

The association of celiac disease and type I diabetes mellitus has been known for some time. This study was undertaken to investigate the prevalence of celiac disease (CD) in diabetic children and adolescents. Eighty-seven patients (44 females, 43 males) aged 218 years, with type I diabetes participated in this study. A group of 87 healthy unrelated girls and boys matched for age and gender ser...

A sequential mucosal prime-boost vaccine regimen of oral attenuated (Att) human rotavirus (HRV) priming followed by intranasal (i.n.) boosting with rotavirus protein VP2 and VP6 rotavirus-like particles (2/6-VLPs) has previously been shown to be effective for induction of intestinal antibody-secreting cell (ASC) responses and protection in gnotobiotic pigs. Because serum or fecal antibody titer...

Previous studies in children have shown that Haemophilus influenzae type b (Hib) polysaccharide conjugate vaccines can reduce nasopharyngeal carriage of H. influenzae and provide herd immunity and suggest that this effect is mediated through mucosal antibodies. As this phenomenon may operate in other invasive bacterial infections which are propagated by nasopharyngeal carriage, mucosal antibody...

The nature of the IgA B cell precursors that receive preferential help from selected clones of T helper cells from mouse Peyer's patches (PP Th A) were studied. Activation of the PP Th A clones required the presence of antigen, sheep erythrocytes (SRBC), in a culture system supporting development of antibody-secreting plasma cells. Two types of PP Th A cells were used. Both gave vigorous IgA re...