Epidermal growth factor (EGF) rapidly stimulates the formation of inositol 1,4,5-trisphosphate in a variety of cell types. Previously we have found that in intact cells stimulation of phospholipase C (PLC) activity by EGF is correlated with the retention of increased amounts of PLC activity by a phosphotyrosine immunoaffinity matrix, suggesting that the EGF-receptor tyrosine kinase phosphorylat...

Background: The main definitions of bronchopulmonary dysplasia (BPD), proposed by Jobe-Bancalari, Shennan et al., and Walsh et al., focus on oxygen (O2)-need and ventilatory support for the first weeks of life and at 36 weeks of post-menstrual age (PMA). Oxygen need at 36 weeks of PMA is sometimes due to intercurrent episodes (IEs) other than BPD. The aim of this retrospective study was to char...

conclusions clonidine plus bupivacaine can increase the duration of motor and sensory block in arthroscopic cruciate ligament repair under spinal anesthesia. however, due to significant hemodynamic changes, further studies are required to determine a safer dose. results all patients were males with a mean age of 24.9 years in group b, and 25.2 years in group bc (p > 0.05). in group bc, time lap...

We survey the evaluation methodology adopted in Information Extraction (IE), as defined in the MUC conferences and in later independent efforts applying machine learning to IE. We point out a number of problematic issues that may hamper the comparison between results obtained by different researchers. Some of them are common to other NLP tasks: e.g., the difficulty of exactly identifying the ef...

background: cox proportional hazard (cph) model is the most widely used model for survival analysis. when there are unobserved/unmeasured individuals factor, then the results of the cox proportional hazard model may not be reliable. the purpose of this study was to compare the results of cph and frailty models in breast cancer (bc) patients. methods: a historical cohort study was carried out us...