OBJECTIVE To test whether pay for performance (P4P) is an effective method to improve adolescent substance use disorder treatment implementation and efficacy. DESIGN Cluster randomized trial. SETTING Community-based treatment organizations. PARTICIPANTS Twenty-nine community-based treatment organizations, 105 therapists, and 986 adolescent patients (953 with complete data). INTERVENTION...

OBJECTIVE This study investigated the effects of continuous positive airway pressure (CPAP) on middle ear pressure and acoustic stapedial reflex and the correlation between CPAP and middle ear pressure. STUDY DESIGN Prospective cohort study. SETTING Tertiary hospitals. SUBJECTS AND METHODS Fifty patients with obstructive sleep apnea-hypopnea syndrome were assigned to the study group, and ...

Introduction This study assessed the long-term outcomes of patients with chest pain (CP) who had attended a Rapid Access Chest Pain Clinic (RACPC) and were by Dobutamine Stress Echocardiography (DSE). Patients in RACPC are now recommended to under cardiac CT first ischaemia testing reserved for those atypical symptoms coronary disease on CTCA or uncertainty about clinical significance ...

BACKGROUND Platelet activation appears to play an important role in thromboembolic complications of infective endocarditis (IE). Mean platelet volume (MPV) is a potentially useful marker of platelet activity and a quick and easy determinant of thrombotic risk. Hence the aim of this study was to investigate the baseline platelet volume indices (MPV and platelet distribution width [PDW]) in IE pa...

A combined theoretical and experimental study of the effect of microhydration on ionization energies (IEs) of thymine is presented. The experimental IEs are derived from photoionization efficiency curves recorded using tunable synchrotron VUV radiation. The onsets of the PIE curves are 8.85 +/- 0.05, 8.60 +/- 0.05, 8.55 +/- 0.05, and 8.40 +/- 0.05 eV for thymine, thymine mono-, di-, and trihydr...

The gene expression of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) was examined in two types of mammalian cells, human HeLa14 and hamster BHK cells. DNA microarray analysis followed by reverse transcription-PCR identified at least 12 viral genes transcribed in both HeLa14 cells and BHK cells inoculated with AcMNPV. 5' rapid amplification of cDNA ends was carried out to examine...