miR-34s keep osteoblasts bone idle T he development of bone-forming osteoblasts is controlled by transcription factors such as Runx2, Osterix, and ATF4, which, in turn, are regulated by a variety of nuclear proteins that inhibit or activate these factors. miRNAs have also been implicated in osteoblast differentiation, though little is known about the effects of individual miRNAs on skeletogenes...

Grid computing has a great potential for grand challenge scientific problems such as Molecular Simulation, High Energy Physics and Genome Informatics. Exploiting under-utilized resources is crucial for a cost-effective, large-scale grid computing platform (i.e., computational grid), but there has been little research work on how to predict what resources will be under-loaded in the near future....

This paper proposes an efficient exact algorithm for the general single-machine scheduling problem where machine idle time is permitted. The algorithm is an extension of the authors’ previous algorithm for the problem without machine idle time, which is based on the SSDP (Successive Sublimation Dynamic Programming) method. We first extend our previous algorithm to the problem with machine idle ...

We model World Wide Web (WWW) servers and clients running over an ATM network using the ABR (available bit rate) service. The WWW servers are modeled using a variant of the SPECweb96 1] benchmark, while the WWW clients are based on a model by Mah 2]. The traac generated by this application is typically bursty, i.e., it has active and idle periods in transmission. A timeout occurs after given am...

Cross-layer approach in cognitive wireless networks is proposed for efficient use of spectrum by detecting primary signals. The detection may be false detection of primary signal, missed detection of primary signal, or correct detection of primary signal. The quick and correct detection of primary signal will be helpful for utilization of the idle spectrum. In the current research, Su’s algorit...

In this paper we present a brokerage system for making idle cpu ressources of anonymous users of the World Wide Web accessble for distributed Web-Computing. The Locust (LOw cost Computing Utilizing Skimmed idle Time) Broker collects and remarkets the aggregated ressources by means of ubiquitious Web and Java technologies and creates an electronic spot market focused on the mainstream Internet u...

Opportunistic spectrum sharing (OSS) is a promising technique to improve spectrum utilization using cognitive radios. Unreliable spectrum sensing by cognitive radios is inevitable in the OSS system. In this paper, we analyze the types of unreliable sensing and their impact on the system performance. The secondary users equipped with cognitive radios sense channels that are unused by the primary...

Power consumption is rapidly increased in data centers because the number of data center is increased and more the scale of data center become larger. Therefore, it is one of key research items to reduce power consumption in data center. The peak power of a typical server is around 250 watts. When a server is idle, it continues to use around 60% of the power consumed when in use, though vendors...

Generally, there are periodic interrupt services in the real-time embedded systems even when the system is in the idle state such as the periodic clock tick interrupts. To minimize the idle power, power management therefore should consider the effect of periodic interrupt services. In this paper, we deal with this problem considering two scenarios. In case the periodic interrupt cannot be disab...

The benefits of Markov-based predictive prefetching have been largely overshadowed by the overhead required to produce high quality predictions. While both theoretical and simulation results for prediction algorithms appear promising, substantial limitations exist in practice. This outcome can be partially attributed to the fact that practical implementations ultimately make compromises in orde...