A retrospective study of 48 patients was conducted to evaluate the efficacy of plasma exchange in children with idiopathic rapidly progressive glomerulonephritis (IRPGN), and renal or non-renal vasculitis. All patients were followed up at a single centre over a 15 year period. Treatment consisted of corticosteroids and/or cytotoxic agents. Plasma exchange was used in all patients because of sev...

the tetrad of bronchial asthma, severe sinusitis, nasal polyp, eosinophilia, and systemic vasculitis is the main feature of allergic granulomatosis and angitis (churg- strauss syndrome). this vasculitis is usually seen idiopathic in patients with a long history of asthma; oral steroids using steroid inhalers, vaccination and desensitization might be triggering factors. drugs such as leukotriene...

an ERM and CNV on initial examination. However, the results of a fundus examination in our patients did not reveal any clinical signs of CNV before ERM surgery. In addition, 1 patient (case 2) underwent FA 1 month after ERM removal, which showed no hyperfluorescence in the macula. We do not believe FA is necessary before performing ERM removal to rule out preexisting CNV. However, FA is valuabl...

OBJECTIVES To evaluate the clinical response after switching from infliximab to adalimumab in patients with Behçet's disease (BD). METHODS In this ongoing, prospective, longitudinal and observational study, data were collected on efficacy and safety of every patient with BD beginning anti-TNF therapy in the last 8 years. The present analysis was restricted to patients who were switched to ada...

Perivasculitis is a common pathological reaction in the retina, the veins being affected more frequently than the arteries. It is not a specific disease entity and the majority of cases are thought to result from an allergic reaction to one of a wide variety of antigens (Ashton, I962). Reviews of the subject have been published by Donders (I958), GoddeJolly (I96I), Doden (I963), Koliopoulos (i9...

Retinal vessels may be affected by inflammatory processes of various origins, usually within the context of uveitis. Retinal vasculitis can lead to vascular occlusion and/or rupture of the blooderetinal barrier, and therefore can be the cause of severe visual loss. Retinal vasculitis is usually defined by the presence of ophthalmoscopically visible whitish perivascular infiltrates. Veins are mo...

A patient with HIV and syphilis presents with bilateral retinal vasculitis and recurrent vitreous hemorrhage. Diagnostic and treatment strategies are discussed.