background: immunological factors are important in pregnancy loss because of the interaction between mother and fetus. t-regulatory cells as the component of humeral immune response play important role in the fetu-maternal interface. one of the regulatory mechanisms for these cells is mediated by antigen independent co-stimulatory signals and interaction of cytotoxic t-lymphocyte antigen 4 (b7/...

OBJECTIVE To study the relationship between semen quality and pregnancy loss in a cohort of couples attempting to conceive. DESIGN Observational prospective cohort. SETTING Not applicable. PATIENT(S) Three hundred and forty-four couples with a singleton pregnancy observed daily through 7 postconception weeks of gestation. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Association betwe...

BACKGROUND Circulating microparticles are markers of cell activation associated with various prothrombotic states. As hypoxia due to uteroplacental thrombosis is considered to be one of the causes of pregnancy loss, microparticles may be associated with pregnancy loss, in addition to, or as part of, other procoagulant states such as antiphospholipid syndrome or hereditary thrombophilias. The ob...

background: normal pregnancy is thought to be dependent on th2 deviation, while recurrent pregnancy loss (rpl) and pre-eclampsia (pe) appear to be biased toward the th1 immune response. it is believed that the soluble form of cd30 (scd30) is an index of th2 immune response or modulator of th1/th2 responses. objective: the aim of this study was determination of the scd30 level in rpl and pe pati...

Recurrent pregnancy loss is a common problem in the reproductive age population of women. It can be caused by many different conditions. This addressed international guidelines that take slightly approach to its diagnosis and treatment. The used this review mainly use Royal College Obstetricians Gynaecologists (RCOG), American Society Reproductive Medicine (ASRM) European Human Reproduction Emb...

Recurrent pregnancy loss may be a consequence of an abnormal embryonic karyotype, or maternal factors affecting the endometrium resulting in defective implantation. In order to study the endometrial factors responsible for recurrent pregnancy loss, endometrial biopsy samples should be precisely timed according to the LH surge, and the investigation should be carried out in a non-conception cycl...