UNLABELLED The insular cortex (IC) and cingulate cortex (CC) are critically involved in pain perception. Previously we demonstrated that fibromyalgia (FM) patients have greater connectivity between the insula and default mode network at rest, and that changes in the degree of this connectivity were associated with changes in the intensity of ongoing clinical pain. In this study we more thorough...

Experiments in animal models indicate that inferior colliculus (IC), the primary auditory midbrain structure, represents sound frequency in a particular spatial organization, a tonotopy, that proceeds from dorsal and superficial to ventral and deeper tissue. Experiments are presented that use high-resolution, sparse-sampling functional magnetic resonance imaging (fMRI) at 3 T to determine if to...

Introduction: Bacterial meningitis is an acute infectious inflammation of the protective membranes covering the brain. Its early diagnosis is vital because of its high morbidity and mortality. It is mostly diagnosed by a gold standard diagnostic tool i.e. Cerebrospinal Fluid (CSF) analysis. However, it is sometimes difficult and or impossible to do this procedure and an alternative diagnostic t...

Background and Purpose: Invasive candidiasis (IC) is a significant cause of morbidity and mortality in patients with hematologic disorders and bone marrow transplant recipients. Rapid, specific and sensitive test for the timely accuracy in immunocompromised patients to reduce mortality rates and prevent IC progress is necessary. We established a real-time PCR assay on blood for the diagnosis an...

in recent years, the development of neuroimaging techniques such as high-resolution magnetic resonance imaging (mri), functional magnetic resonance imaging (fmri), positron emission tomography (pet), or single photon emission tomography (spect) has promoted the identification of structural and functional characteristics underlying mental disorders to a great extent. in anxiety disorders, recent...

Abstract Background Iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. Severe iron deposition in tissues leads to organ dysfunction. Many organs can be affected such as heart, liver, and endocrine organs. Cardiac failure and liver fibrosis are the consequent of Iron overload in transfusion dependent hemoglobinopathy. Magne...

Chemical investigation of Garcinia eugenifolia and Calophyllum enervosum yielded six compounds. One of these was found to be a novel compound identified as enervosanone. Five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. These compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. Antimicrobial...

chemical investigation of garcinia eugenifolia and calophyllum enervosum yielded six compounds. one of these was found to be a novel compound identified as enervosanone. five known compounds cambogin, epicatechin, osajaxanthone, rubraxanthone and isocowanol, were also isolated. these compounds were tested for their bioactivity as antimicrobial, antioxidant and cytotoxicagents. antimicrobial ass...

One of the main challenges in developing magnetic resonance imaging (MRI) systems is to create a static coil that needs to generate magnetic field density along with the characteristics of optimal homogeneity and magnitude size. To do this, two N42 Block PMs are used and the iron core is designed and optimized in accordance with the dimensions of PM pieces using ANSYS Maxwell software. Then, al...

Introduction: Along with the increased use of cardiac imaging at clinics there is increased attention to the potential risks related to the methods used like magnetic resonance (MR) and it cannot be ruled out that MR can alter DNA structure. The aim of this review is to assess the impact of routine cardiac magnetic resonance (CMR) scanning on DNA damages in human T lymphocytes....