Here we report on the clinical findings and key symptoms in WNT10A-related ectodermal dysplasias. The ectodermal dysplasias (ED) are a large, heterogeneous group of disorders characterized by defects in the morphogenesis of skin, sweat, sebaceous, submucous, and mammary glands, hair, nails and teeth. Numerous more or less distinct entities have been reported, however, most of them are very rare...

Boys with X-linked hypohidrotic ectodermal dysplasia and their families were studied. Many suffered severe illness in early childhood and nearly 30% died; many had feeding problems, severe fever, atopic disease, and recurrent respiratory infections. Some infants failed to thrive. We found no consistent common endocrine or immunological abnormality, although, most had abnormal immunoglobulin pro...

The 16O, 17O and 18O abundances of howardites, eucrites, and diogenites have been used to assign them to a single ‘HED’ parent body, thought to be asteroid 4 Vesta. We report the first evidence of oxygen isotopic heterogeneity among HED meteorites indicating incompletely mixed sources. New high-precision oxygen isotope measurements of 34 HED meteorites reveal that most have the same v17OP, cons...