نتایج جستجو برای: hypertriglyceridemia

تعداد نتایج: 4872  

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2005
Claudio Priore Oliva Livia Pisciotta Giovanni Li Volti Maria Paola Sambataro Alfredo Cantafora Antonella Bellocchio Alberico Catapano Patrizia Tarugi Stefano Bertolini Sebastiano Calandra

OBJECTIVE Mutations in LPL or APOC2 genes are recognized causes of inherited forms of severe hypertriglyceridemia. However, some hypertrigliceridemic patients do not have mutations in either of these genes. Because inactivation or hyperexpression of APOA5 gene, encoding apolipoprotein A-V (apoA-V), causes a marked increase or decrease of plasma triglycerides in mice, and because some common pol...

2015
Minyong Kang Chang Wook Jeong Ja Hyeon Ku Choel Kwak Hyeon Hoe Kim

OBJECTIVES Many previous studies have suggested that the outcome of prostate cancer (PCa) may be closely related to abnormal lipid metabolism. Therefore, in this study, we evaluated the preoperative lipid profiles of patients with clinically localized prostate cancer (PCa) who underwent radical prostatectomy (RP), with particular emphasis on the relationship between these profiles and biochemic...

Journal: :BMC Pregnancy and Childbirth 2004
Elaine C Tsai Judy A Brown Megan Y Veldee Gregory J Anderson Alan Chait John D Brunzell

BACKGROUND: Pregnancy in patients with lipoprotein lipase deficiency is associated with high risk of maternal pancreatitis and fetal death. A very low fat diet (< 10% of calories) is the primary treatment modality for the prevention of acute pancreatitis, a rare but potentially serious complication of severe hypertriglyceridemia. Since pregnancy can exacerbate hypertriglyceridemia in the geneti...

2017
Daisaku Masuda Shizuya Yamashita

Fasting hypertriglyceridemia is positively associated with the morbidity of coronary heart disease (CHD), and postprandial (non-fasting) hypertriglyceridemia is also correlated with the risk status for CHD, which is related to the increase in chylomicron (CM) remnant lipoproteins produced from the intestine. CM remnant particles, as well as oxidized low density lipoprotein (LDL) or very low den...

Journal: :The Chinese journal of physiology 2007
Hung-Jung Lin Ching-Hui Loh Min-Tser Liao Tse-Tsung Liu Po-Shiuan Hsieh

This study was designed to compare the pressor response to hypertriglyceridemia under basal glucose and insulin condition as well as the decay pattern of this lipid-induced pressor effect in normal (NRs) and fructose-induced insulin resistant rats (FIRs). The rats were on a fructose-enriched or a regular chow diet for 8 wks and then were further divided into two subgroups (n = 8/group) with lip...

Journal: :Biological & pharmaceutical bulletin 2002
Tomoyuki Mine Kyoko Miura Yoshiro Kitahara Akira Okano Ryuzo Kawamori

Postprandial hypertriglyceridemia, as well as postprandial hyperglycemia, are important factors contributing to the development of cardiovascular disease in patients with type 2 diabetes. Nateglinide is a recently approved antidiabetic that suppresses postprandial hyperglycemia by stimulating the early phase of insulin secretion. In the present study, we investigated the effects of nateglinide ...

2013
Mi Sun Lim Chang Won Choi Beyong Il Kim Hye Ran Yang

PURPOSE Preterm infants on parenteral nutrition are at a relatively high risk for hypertriglyceridemia because they have immature lipoprotein lipase activity. The purpose of this study was to analyze the clinical factors affecting lipid metabolism in preterm infants receiving parenteral nutrition and to evaluate the influence of intravenous heparin on serum triglycerides to determine the adequa...

Journal: :Journal of lipid research 2012
Tomomi Yamazaki Kyoko Kishimoto Osamu Ezaki

Postprandial hyperlipidemia (lipemia) is a risk factor for atherosclerosis. However, mouse models of postprandial hyperlipidemia have not been reported. Here, we report that ddY mice display marked postprandial hypertriglyceridemia in response to dietary fat. In ddY mice, the fasting serum total triacylglyceride (TG) concentration was 134 mg/dl, which increased to 571 mg/dl after an intragastri...

Journal: :Arteriosclerosis 1982
U Beil S M Grundy J R Crouse L Zech

To determine mechanisms of elevated plasma triglycerides (TG) in patients with primary hypertriglyceridemias, simultaneous studies were carried out on kinetics of very low density lipoprotein-triglycerides (VLDL-TG) and synthesis of cholesterol and bile acids. Sixteen hypertriglyceridemic patients with familial combined hyperlipidemia (FCHL) and 12 patients with poorly classified, primary hyper...

Journal: :Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2008
Crésio de Aragão Dantas Alves Daniela Seabra Lima

This article aims to review the physiopathology, diagnosis and treatment of cystic fibrosis-related dyslipidemia (CFD). Bibliographic searches of the Medline and Latin American and Caribbean Health Sciences Literature databases were made (year range, 1987-2007), and the most representative papers on the theme were selected. The characteristic symptoms of CFD are hypertriglyceridemia-with or wit...

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