OBJECTIVE To evaluate the efficacy of using hyperbaric oxygen to enhance auricular composite graft survival via a prospective, randomized, placebo-controlled, double-blind study. DESIGN Eighteen New Zealand White rabbits were randomly assigned to treatment (n = 9) and control (n = 9) groups after amputation and reattachment of 20 x 10-mm auricular composite grafts. The treatment group receive...

A 58-year-old man presented with a change in vision during hyperbaric oxygen (HBO) therapy. Subsequent follow-up visits showed a hypermetropic shift, which succeeded the myopic shift after each of two series of HBO treatments. The maximal refractive amplitude was 3.00 D (range -1.37 D to +1.62 D) in the right eye and 2.75 D (range -1.25 D to + 1.50 D) in the left eye. Refraction stabilized afte...

Lyme disease is the most commonly reported vector-borne illness in the United States, but it is relatively rare in Taiwan. Lyme disease can be treated with antibiotic agents, but approximately 20% of these patients experience persistent or intermittent subjective symptoms, so-called chronic Lyme disease (CLD). The mechanisms of CLD remain unclear and the symptoms related to CLD are difficult to...

Hyperbaric oxygen therapy continues to be discussed as another adjunctive therapy in the continuum of wound care. There is a dearth of evidence from randomized clinical trials on HBO therapy. For evidence-based practice, more randomized, controlled studies need to be conducted with HBO therapy to determine its efficacy in treating other chronic wounds besides those of patients with diabetes.

The effect on the human lens of prolonged hyperbaric oxygen therapy is reported. Eye examinations were given to 25 patients before, during, and after a series of 150 or more exposures to hyperbaric oxygen. All patients changed refraction in the direction of myopia during treatment. Fifteen of the patients had clear lens nuclei before treatment. Seven of these developed a nuclear cataract with r...

Wound healing is a complex process that proceeds through a number of welldefined and orchestrated stages: inflammation, proliferation, matrix deposition, and remodeling (1,2). Enzymatic remodeling of the extracellular matrix (ECM) is considered essential for proper wound healing (3). Various types of proteinases are implicated in ECM degradation, with the major enzymes represented by matrix met...

PURPOSE This study was to observe the clinical effects of hyperbaric oxygen therapy combined with supragingival and subgingival scaling therapy on periodontitis. METHODS The patients with periodontitis were divided randomly into 3 groups, the supragingival and subgingival scaling therapy group, the hyperbaric oxygen therapy group, the hyperbaric oxygen combined with supragingival and subgingi...

Introduction Hyperbaric oxygen (HBO) has been suggested to be beneficial in inflammatory bowel syndromes, mainly in Crohn’s disease, on the assumption that enteric tissue oxygenation is impaired. Several reports have shown encouraging results on the use of HBO in patients with severe or recurrent perineal CD [1-5]. The role of HBO in the pathogenesis of CD has to be determined in order to expla...

This paper presents results on the effect of a single session of hyperbaric oxygenation (HBO) therapy on prevalence zone of ischemia and myocardial necrosis in experimental animals. Compared with "high-doses" of HBO therapy, application of the so-called "small" doses (oxygen pressure at 0.02 MPa) was more favorable. The results of this study suggest the effectiveness of HBO in irreversible obst...

BACKGROUND AND PURPOSE Hyperbaric oxygen therapy (HBO) has promise as a treatment for acute stroke. This study was conducted to evaluate the efficacy, safety, and feasibility of using HBO in acute ischemic stroke. METHODS We conducted a randomized, prospective, double-blind, sham-controlled pilot study of 33 patients presenting with acute ischemic stroke who did not receive thrombolytics over...