Aim: Topical drug delivery of fluconazole, an antifungal drug, in gel form was formulated to avoid the side effect of the oral route. Methodology: Different polymers; Sodium carboxymethyl cellulose, Sodium alginate, Carbopol 934P, Hydroxypropylmethyl cellulose, Pluronic F-127 and hydroxypropyl cellulose, were used. The compatibility of fluconazole and different gelling polymer was assessed thro...

The cover image by Valeria De Matteis, Alessandro Cannavale, Marco Pugliese, and Umberto Berardi summarizes the different features of a new, multifunctional “thermoelectrochromic” device. Its architecture is based on hydroxypropyl cellulose electrolyte, which allows for passive thermochromic transition from transparent state to milky, reflective once critical temperature 43°C attained; simultan...

Purpose of Study: In the present study, an attempt was made to design and evaluate buccoadhesive bilayer tablets of granisetron hydrochloride (an anti-emetic drug), in order to overcome bioavailability problems, to reduce dose dependent side effects and frequency of administration. Method: Bilayer buccal tablets containing the drug were prepared by direct compression method using combination of...

The effect of oil concentration (from 5 to 47%) and type cellulose ether on the rheological properties (flow linear viscoelasticity), microstructure digestion in o/w emulsions were investigated study. Three types ethers used: a hydroxypropyl methylcellulose (HPMC) two methylcelluloses (MC) with different degrees methoxyl content. All showed shear thinning behaviour. increase emulsion's viscosit...

Hydroxypropyl starch was synthesized by modified sago starch with hydroxypropylation reaction. Hydroxypropyl starch nanoparticles with mean particle sizes of 110 nm are obtained by controlled precipitation through the drop-wise addition of dissolved hydroxypropyl starch solution into excess absolute ethanol. Piperine was loaded onto hydroxypropyl starch nanoparticles and native starch nanoparti...

This study aimed to produce a gastroretentive floating tablet of Metoprolol succinate and examine the effects release retardant on in vitro drug release. is β1 selective antagonist used as an Anti-hypertensive, Antiarrhythmic, Anti Angina. has 48% oral bioavailability due limited absorption from lower gastrointestinal tract. The tablets were designed increase stomach retention, prolong release,...

Large amounts of wastewater containing hydroxypropyl guar gum (HPGG), polyacrylamide (PAM) and carboxymethyl cellulose (CMC) are produced in the process fracturing. In work, a Fentonlike system presence H2O2 was employed to degrade wastewater. The effects oxidant concentration, catalyst dosage, temperature pH on degradation efficiency polymer were studied detail. Results showed that prepared co...

Second-degree burns have the highest prevalence and often occur in household environment. The healing process can be accelerated by traditional medicine. One of many plants known to wound-healing abilities is Binahong plant (Anredera cordifolia (Ten.) Steenis). gel preparation chosen because benefits it provide. gelling agents used were Hydroxypropyl Methyl Cellulose Hydroxyethyl Cellulose. com...