نتایج جستجو برای: hydrophilic drug
تعداد نتایج: 602623 فیلتر نتایج به سال:
فرمولاسیون و بررسی خصوصیات پراکندگی های جامد پیروکسیکام تهیه شده با پلی اتیلن گلیکول 4000 و توئین 40
Background and purpose: Piroxicam is a non-steroidal anti- inflammatory drug that is characterized by low solubility and high permeability. According to the biopharmaceutic drug classification system, piroxicam is a class 2 drug with low solubility and high permeability. The solid dispersion, ammroach is commonly used to improve the dissolution of poorly water soluble drugs using hydrophilic po...
The purpose of this work was to develop once daily sustained release (SR) matrix tablets of naproxen, an anti-inflammatory agent. The tablets were prepared by wet granulation method along with hydrophilic matrix materials like Methocel K 15M CR and Methocel K 100M CR. The granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. The ...
the interaction of drugs and polymers used to incorporate in or surface modify/coat the liposomes can affect the phase transition, fluidity and other physical properties as well as in vivo fate of vesicles. in this study, differential scanning calorimetry (dsc) was used to investigate changes in the temperature and the enthalpy of phase transition of liposomes of various electrical charges foll...
a microporous bisphenol a diglycidyl ether (dgeba) epoxified-polyethersulfone (pes) blend membrane (epes membrane) was prepared through dry-wet phase inversion. this study attempts to correlate the changes in membrane physical and chemical properties when the epes membranes were exposed to different durations of dry-phase inversion, towards the separation efficiency of carcinogen chromium (vi)....
311 ©2011 Society For Biomaterials
An Investigation into the Effect of Carbopols on the Release of Propranolol HCl from Tablet Matrices
In this study, attempts were made to evaluate the effect of various acrylic acid based Carbopols on the release profile of a beta-adrenoreceptor blocking drug, propranolol HCl, from matrix-type tablets invitro. For this purpose, tablets containing 160 mg of propranolol HCl along with various amounts of Carbopols 934 (C934), 971 (C971), 974 (C974) and Pemulen (Pem) were prepared using the wet gr...
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