BACKGROUND Hydrodynamic injection is an effective method for DNA delivery in mouse liver and is being translated to larger animals for possible clinical use. Similarly, phiC31 integrase has proven effective in mediating long-term gene therapy in mice when delivered by hydrodynamic injection and is being considered for clinical gene therapy applications. However, chromosomal aberrations have bee...

Hydrodynamic model generally deals with enormous amount of data and utilizes huge computational resources for simulation. Powerful and robust servers with extensive storage capabilities are therefore desirable for rapid simulation. Unfortunately, it is not always possible for an individual to effort those kind of facilities whereas a central computer system can be the viable alternative to serv...

Self-propelled colloids (swimmers) in confining geometries follow trajectories determined by hydrodynamic interactions with the bounding surfaces. However, typically these interactions are ignored or truncated to the lowest order. We demonstrate that higher-order hydrodynamic moments cause rod-like swimmers to follow oscillatory trajectories in quiescent fluid between two parallel plates, using...

Bushehr Bay is situated along the northern Iranian coasts of the Persian Gulf, between 28°52΄ and 29°5΄ north latitude and 50°42΄ and 50°52΄east longitude. In this study COHERENS, which is a threedimensional hydrodynamic model, was employed to simulate surface and under surface currents in the Bushehr Bay. The atmospheric forces and four main tidal constituents M2, S2, K1, O1 and also boundary ...

The flexible and greatly expanded roughly spherical model for mucus glycoproteins proposed earlier, on the basis of hydrodynamic and n.m.r. data, is supported by new hydrodynamic results on a bronchial glycoprotein from a cystic-fibrosis patient. Furthermore, images from electron microscopy of this molecule and a lower-molecular-weight mucus glycoprotein (which closely resembles a glycopolypept...

in coastal areas, hydrodynamic factors make changes in shorelines geomorphology. this can affect coastal facilities and cause hazards to human societies in the areas. this study has investigated the influence of wave and tide properties on khamir port, hormoz strait in coast of persian gulf. the purpose of the study is to make a mathematical regional and local modeling of water level fluctuatio...

New 2-phenylpyridazinones, analogs o f 4-chloro-5-methylamino-2-phenylpyridazin-3(2H)ones, were assayed for their phytotoxic activity to interfere with plant pigment formation. Six derivatives with — SCF3, — OCF2CH FCF3, — O CH F2, — CN, or — Br in meta position o f the phenyl ring exhibited similar or better bleaching activity than the m -CF3 analog (norflurazon). The activity is predominantly...

For the needs of high electron mobility transistors (HEMTs) optimization a reliable software simulation tool is required. Due to the high electric field in the device channel a hydrodynamic approach is used to properly model the electron transport. We modify an existing hydrodynamic mobility model in order to achieve a better agreement with Monte Carlo (MC) simulation data and measured DC and A...

The complete 3D nonlinear dynamic problem of extensible, flexible risers conveying fluid is considered. For describing the dynamics of the system, the Newtonian derivation procedure is followed. The velocity field inside the pipe formulated using hydrostatic and Bernoulli equations. The hydrodynamic effects of external fluids are taken into consideration through the nonlinear drag forces in var...

The nonlinear self-interaction of an electrostatic surface wave on a semibounded quantum plasma with relativistic degeneracy is investigated by using quantum hydrodynamic (QHD) model and the Poisson’s equation with appropriate boundary conditions. It is shown that a part of the second harmonic generated through self-interaction does not have a true surface wave character but propagates obliquel...